Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284444 | 0.83 | HTT (0.46) | HTTTP53TSHRLMNAFABP4 | |
| SCHEMBL3243207 | 0.81 | POLB (0.46) | HTTTP53TSHRLMNA | |
| SCHEMBL3581192 | 0.79 | CA12 (0.52) | HTTTSHRLMNAL3MBTL1 | |
| SCHEMBL18424881 | 0.77 | HTT (0.41) | HTTTP53TSHRLMNAFABP4 | |
| SCHEMBL23089860 | 0.76 | HTT (0.43) | HTTTP53TSHRLMNAFABP4 | |
| SCHEMBL4111848 | 0.76 | HTT (0.40) | HTTTP53TSHRLMNAFABP4 | |
| SCHEMBL3432500 | 0.76 | HTT (0.40) | HTTTP53TSHRLMNAFABP4 | |
| SCHEMBL6300741 | 0.76 | HTT (0.58) | HTTTP53TSHRLMNAFABP4 | |
| SCHEMBL1157477 | 0.76 | HTT (0.58) | HTTTP53TSHRLMNAFABP4 | |
| SCHEMBL25168185 | 0.75 | HTT (0.39) | HTTTP53TSHRLMNAFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120077027-A | Sulfonylimide compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社钟根堂 | 2025-05-30 | — | — | CN | disclosed |
| US-8183380-B2 | 2-aminoquinolines | HOFFMANN-LA ROCHE INC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-20090227570-A1 | 2-AMINOQUINOLINES | HOFFMANN-LA ROCHE, INC. | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227570-A1 | 2-AMINOQUINOLINES | HTR5A, HTR2C, HTR2A | HTT 1042/4885TP53 4118/4885TSHR 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.