Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734851 | 0.82 | POLB (0.36) | CYP11B1CYP11B2KMT2AHSD17B1CYP2D6 | |
| SCHEMBL9733870 | 0.82 | NPC1 (0.48) | CYP11B1CYP11B2KMT2ACYP1A2NPC1 | |
| SCHEMBL9737121 | 0.76 | ALDH1A1 (0.40) | KMT2AHSD17B1CYP2D6CYP1A2POLB | |
| SCHEMBL13845754 | 0.75 | NPC1 (0.37) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL17902676 | 0.74 | CYP2D6 (0.40) | CYP11B1CYP11B2KMT2AHSD17B1CYP2D6 | |
| SCHEMBL1254599 | 0.73 | CYP2D6 (0.49) | CYP11B1CYP11B2KMT2AHSD17B1CYP2D6 | |
| SCHEMBL17694177 | 0.73 | KMT2A (0.40) | CYP11B1CYP11B2KMT2AHSD17B1CYP2D6 | |
| SCHEMBL534241 | 0.72 | CYP2D6 (0.55) | CYP11B1CYP11B2KMT2ACYP2D6POLB | |
| SCHEMBL11241585 | 0.72 | CYP2D6 (0.55) | CYP11B1CYP11B2KMT2ACYP2D6POLB | |
| SCHEMBL8344022 | 0.72 | NPC1 (0.53) | NPC1CASP3RAB9ASENP8NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118157-A1 | Processes For Production Of Wine Lactone And Its Intermediates And Application Of The Lactone | SAN-EI GEN F.F.I. INC. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20090118157-A1 | Processes For Production Of Wine Lactone And Its Intermediates And Application Of The Lactone | SAN-EI GEN F.F.I. INC. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20090118157-A1 | Processes For Production Of Wine Lactone And Its Intermediates And Application Of The Lactone | SAN-EI GEN F.F.I. INC. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20080153817-A1 | Treatment for Alzheimer's Disease and Related Conditions | MERCK SHARP & DOHME LTD. (GB) | 2008-06-26 | — | — | US | disclosed |
| EP-1787975-A1 | PROCESSES FOR PRODUCTION OF WINE LACTONE AND ITS INTERMEDIATES AND APPLICATION OF THE LACTONE | SAN-EI GEN F.F.I., INC. (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-5137035-A | With combustible filler of natural tobacco, reconstituted tobacco or tobacco substitutes | PHILIP MORRIS INCORPORATED (US) | 1992-08-11 | — | — | US | disclosed |
| US-5114493-A | Smoking compositions containing a hexahydrobenzofuranone flavorant | PHILIP MORRIS INC. (US) | 1992-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153817-A1 | Treatment for Alzheimer's Disease and Related Conditions | PSEN1, PSEN2, APP | CYP11B1 295/4885CYP11B2 320/4885KMT2A 4062/4885 |
| US-20090118157-A1 | Processes For Production Of Wine Lactone And Its Intermediates And Application Of The Lactone | DCXR, COASY, AKR7A2 | CYP11B1 83/4885CYP11B2 162/4885KMT2A 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.