SCHEMBL4103170

SCHEMBL4103170

CCCC(=O)OC[C@H]1CN(c2ccc3c(C)noc3c2)C(=O)O1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.42
GRM2 Q14416 10/20 0.40
MAOA P21397 3/20 0.40
NLRP3 Q96P20 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4101915 0.82 MAOB (0.58) MAOBGRM2MAOA
SCHEMBL4101914 0.82 MAOB (0.58) MAOBGRM2MAOA
SCHEMBL4108969 0.81 MAOB (0.44) MAOBGRM2MAOA
SCHEMBL4111759 0.81 MAOB (0.44) MAOBGRM2MAOA
SCHEMBL13697394 0.80 F10 (0.47) MAOBGRM2MAOA
SCHEMBL4108936 0.80 MAOA (0.50) MAOBMAOA
SCHEMBL4108508 0.80 MAOA (0.50) MAOBMAOA
SCHEMBL4108932 0.80 MAOA (0.50) MAOBMAOA
SCHEMBL4108504 0.80 MAOA (0.50) MAOBMAOA
Hydrochloric Acid SCHEMBL4111748 0.79 F10 (0.46) MAOBGRM2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090221655-A1 ANTIBACTERIAL AGENTS PITZER, INC. (US) 2009-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221655-A1 ANTIBACTERIAL AGENTS OXSR1, CBR3, AOC3 MAOB 1705/4885GRM2 4556/4885MAOA 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.