Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | GLA | P06280 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22222297 | 0.90 | KMT2A (0.66) | KDM4EALDH1A1GLASMN1; SMN2POLB | |
| SCHEMBL9668420 | 0.88 | ALDH1A1 (0.74) | KDM4EALDH1A1GLASMN1; SMN2POLB | |
| SCHEMBL1966824 | 0.88 | KDM4E (0.74) | KDM4EALDH1A1GLASMN1; SMN2POLB | |
| SCHEMBL8497095 | 0.87 | ALDH1A1 (0.65) | KDM4EALDH1A1GLASMN1; SMN2MEN1 | |
| SCHEMBL7279400 | 0.86 | ALDH1A1 (0.72) | KDM4EALDH1A1GLASMN1; SMN2MEN1 | |
| SCHEMBL10383114 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1GLASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL11451398 | 0.86 | KDM4E (0.72) | KDM4EALDH1A1GLASMN1; SMN2MEN1 | |
| SCHEMBL7435099 | 0.85 | ATM (0.76) | KDM4EALDH1A1GLASMN1; SMN2POLB | |
| SCHEMBL3945922 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1GLASMN1; SMN2POLB | |
| SCHEMBL9069985 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1GLASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221829-A1 | 3,4-Dihydroisoquinolinium Salt Derivatives | HANWHA CHEMICAL CORPORATION (KR) | 2009-09-03 | — | — | US | disclosed |
| WO-2008078871-A1 | 3,4-DIHYDROISOQUINOLINIUM SALT DERIVATIVE COMPOSITION HAVING NEMATICIDAL EFFECT ON B. XYLOPHILUS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2008-07-03 | — | — | WO | disclosed |
| EP-1896419-A1 | 3,4-DIHYDROISOQUINOLINIUM SALT DERIVATIVES | HANWHA CHEMICAL CORPORATION (KR) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006129978-A1 | 3,4-DIHYDROISOQUINOLINIUM SALT DERIVATIVES | HANWHA CHEMICAL CORPORATION (KR) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221829-A1 | 3,4-Dihydroisoquinolinium Salt Derivatives | KCNQ3, KCNQ1, KCNQ2 | KDM4E 1933/4885ALDH1A1 369/4885GLA 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.