Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 8/20 | 0.42 |
| ▸ | CDC25A | P30304 | 7/20 | 0.42 |
| ▸ | S100A4 | P26447 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 5/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hypochlorous Acid SCHEMBL4115442 | 0.77 | MAPT (0.48) | CDC25BCDC25AS100A4KDM4EALDH1A1 | |
| Hypochlorous Acid SCHEMBL4116617 | 0.77 | CDC25B (0.40) | CDC25BCDC25AS100A4KDM4EALDH1A1 | |
| SCHEMBL5822470 | 0.68 | CDC25B (0.50) | CDC25BCDC25AS100A4KDM4EALDH1A1 | |
| SCHEMBL10446607 | 0.67 | CDC25B (0.49) | CDC25BCDC25AS100A4KDM4EALDH1A1 | |
| SCHEMBL4110933 | 0.67 | CDC25B (0.49) | CDC25BCDC25AS100A4KDM4EALDH1A1 | |
| SCHEMBL22874151 | 0.67 | CDC25B (0.54) | CDC25BCDC25AS100A4KDM4EALDH1A1 | |
| Hypochlorous Acid SCHEMBL4113963 | 0.67 | MAPT (0.57) | CDC25BCDC25AS100A4KDM4EALDH1A1 | |
| SCHEMBL1671378 | 0.66 | CDC25B (0.44) | CDC25BCDC25AS100A4KDM4EALDH1A1 | |
| SCHEMBL29941466 | 0.65 | CDC25B (0.68) | CDC25BCDC25AS100A4KDM4EALDH1A1 | |
| SCHEMBL571026 | 0.65 | CDC25B (0.68) | CDC25BCDC25AS100A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247472-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | FLUOFARMA (FR) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247472-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | CCNA1, MKI67, CCNT1 | CDC25B 90/4885CDC25A 14/4885S100A4 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.