Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 11/20 | 0.54 |
| ▸ | CDC25A | P30304 | 10/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | MAP2K7 | O14733 | 3/20 | 0.52 |
| ▸ | S100A4 | P26447 | 6/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.46 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822470 | 0.83 | CDC25B (0.50) | CDC25BCDC25AAURKAAURKBMAP2K7 | |
| SCHEMBL21796068 | 0.81 | ALDH1A1 (0.42) | CDC25BCDC25AAURKAAURKBPTPN1 | |
| SCHEMBL571026 | 0.80 | CDC25B (0.68) | CDC25BCDC25AAURKAAURKBMAP2K7 | |
| SCHEMBL29941466 | 0.80 | CDC25B (0.68) | CDC25BCDC25AAURKAAURKBMAP2K7 | |
| SCHEMBL10446607 | 0.78 | CDC25B (0.49) | CDC25BCDC25AAURKAAURKBMAP2K7 | |
| Water SCHEMBL8664586 | 0.78 | CDC25B (0.65) | CDC25BCDC25AAURKAAURKBMAP2K7 | |
| SCHEMBL7915423 | 0.77 | CDC25B (0.48) | CDC25BCDC25AAURKAAURKBMAP2K7 | |
| SCHEMBL9627396 | 0.76 | IDO1 (0.62) | CDC25BCDC25AS100A4PTPN1MEN1 | |
| SCHEMBL15491792 | 0.75 | CDC25B (0.62) | CDC25BCDC25AAURKAAURKBMAP2K7 | |
| SCHEMBL5811059 | 0.74 | CDC25B (0.47) | CDC25BCDC25AMAP2K7S100A4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332427-B2 | Menaquinol compositions and methods of treatment | Epizon Pharma, Inc. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210009494-A1 | Menaquinol Compositions and Methods of Treatment | Epizon Pharma, Inc. (US) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009494-A1 | Menaquinol Compositions and Methods of Treatment | SDHA, SDHB, NDUFB7 | CDC25B 1416/4885CDC25A 1558/4885AURKA 2334/4885 |
| US-11332427-B2 | Menaquinol compositions and methods of treatment | SDHA, SDHB, NDUFB7 | CDC25B 1416/4885CDC25A 1558/4885AURKA 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.