Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753302 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL17179161 | 0.81 | CYP1A2 (0.80) | HMGCRCYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL11139452 | 0.79 | HMGCR (0.80) | HMGCRCYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL416646 | 0.79 | HMGCR (0.80) | HMGCRCYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL410681 | 0.79 | HMGCR (0.80) | HMGCRCYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL414271 | 0.79 | HMGCR (0.80) | HMGCRCYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL8763744 | 0.79 | HMGCR (0.80) | HMGCRCYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL18746575 | 0.79 | LMNA (0.42) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL411385 | 0.79 | HMGCR (0.80) | HMGCRCYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL2553133 | 0.79 | HMGCR (0.80) | HMGCRCYP1A2CYP2D6MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8663902-B2 | Laser imaging | DATALASE LTD (GB) | 2014-03-04 | — | — | US | disclosed |
| EP-2414895-B1 | LASER IMAGING | DATALASE LTD (GB) | 2013-11-06 | — | — | EP | disclosed |
| EP-2414895-A1 | LASER IMAGING | DataLase Ltd (GB) | 2012-02-08 | — | — | EP | disclosed |
| US-20120021362-A1 | Laser Imaging | DATALASE LTD. (GB) | 2012-01-26 | — | — | US | disclosed |
| WO-2010112940-A1 | LASER IMAGING | DATALASE LTD. (GB) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010089595-A1 | CO-CRYSTALS AND THEIR USE | DATALASE LTD. (GB) | 2010-08-12 | — | — | WO | disclosed |