Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20451503 | 0.91 | NPC1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL500633 | 0.85 | GPR84 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL27981705 | 0.84 | NPC1 (0.37) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL500634 | 0.83 | GPR84 (0.34) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30297029 | 0.83 | GPR84 (0.34) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL12773216 | 0.80 | GPR84 (0.36) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL374595 | 0.79 | NPC1 (0.40) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL29631959 | 0.79 | NPC1 (0.40) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL5080716 | 0.79 | NPC1 (0.44) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL20599274 | 0.78 | PTPN5 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088171-A1 | EYEGLASS LENS | Teijin Chemicals, Ltd. (JP) | 2009-08-12 | — | — | EP | disclosed |