⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332434 | 0.72 | — | — | |
| SCHEMBL16190137 | 0.72 | — | — | |
| SCHEMBL4112952 | 0.72 | ALDH1A1 (0.52) | — | |
| SCHEMBL6424422 | 0.70 | — | — | |
| SCHEMBL8115090 | 0.70 | — | — | |
| SCHEMBL20285553 | 0.65 | PTGS1 (0.37) | — | |
| SCHEMBL367014 | 0.65 | — | — | |
| SCHEMBL6002314 | 0.64 | — | — | |
| SCHEMBL23438235 | 0.60 | — | — | |
| SCHEMBL11443724 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005769-B2 | 2,3-dihydrobenzofuran-5YL compounds as DYRK kinase inhibitors | 4SC AG (DE) | 2018-06-26 | — | — | US | disclosed |
| US-20160137637-A1 | 2,3-DIHYDROBENZOFURAN-5YL COMPOUNDS AS DYRK KINASE INHIBITORS | 4SC DISCOVERY GMBH (DE) | 2016-05-19 | — | — | US | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20080076771-A1 | Thrombopoietin Receptor Agonists | REITER LAWRENCE A | 2008-03-27 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-0815093-B1 | HERBICIDE FLUOROTHIADIAZOLYL OXYACETAMIDES | BAYER AG (DE) | 2000-08-16 | — | — | EP | disclosed |
| US-5858922-A | SELECTIVE CONTROL OF WEEDS IN CROPS, ESPECIALLY PREEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-12 | — | — | US | disclosed |
| EP-0815093-A1 | HERBICIDE FLUOROTHIADIAZOLYL OXYACETAMIDES | BAYER AG (DE) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996028434-A1 | HERBICIDE FLUOROTHIADIAZOLYL OXYACETAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-19 | — | — | WO | disclosed |