⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17165161 | 0.97 | — | — | |
| SCHEMBL222064 | 0.56 | — | — | |
| SCHEMBL4446556 | 0.52 | — | — | |
| SCHEMBL559639 | 0.52 | — | — | |
| SCHEMBL4446554 | 0.52 | — | — | |
| SCHEMBL4437229 | 0.52 | — | — | |
| SCHEMBL6182164 | 0.52 | — | — | |
| SCHEMBL626537 | 0.52 | — | — | |
| SCHEMBL2797109 | 0.52 | — | — | |
| SCHEMBL4437233 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13080 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| US-20240109866-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2024-04-04 | — | — | US | claimed |
| EP-3568390-B1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) | 2024-03-06 | — | — | EP | claimed |
| CN-112368289-B | C26-linked rapamycin analogues as MTOR inhibitors | 锐新医药公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117377674-A | Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders | 大塚制药株式会社 | 2024-01-09 | — | — | CN | claimed |
| CN-117337175-A | Combination Therapy for Cancer Treatment | 密歇根大学董事会 | 2024-01-02 | — | — | CN | claimed |
| CN-114126713-B | Substituted benzimidazolone compounds | 百时美施贵宝公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117186062-A | 4-carbonylaminoisoindoline-1, 3-dione compound, preparation method, pharmaceutical composition and application thereof | 天津谷堆生物医药科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117186061-A | 4-carbonylaminoisoindolin-1-one derivatives, compositions comprising the same, and methods of use | 天津谷堆生物医药科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117157299-A | Tricyclic heterocyclic derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2023-12-01 | — | — | CN | claimed |
| WO-2004005281-A1 | INHIBITORS OF TYROSINE KINASES | NOVARTIS AG (CH) | 2004-01-15 | — | — | WO | claimed |
| US-6432964-B1 | A THIENYLPYRIMIDINE COMPOUND | AGREVO UK LIMITED (GB) | 2002-08-13 | — | — | US | claimed |
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | claimed |
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | claimed |
| US-5874424-A | Inhibitors of interleukin-1β converting enzyme | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1999-02-23 | — | — | US | claimed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | claimed |
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | claimed |
| EP-0655062-B1 | MORPHOLINO/THIOMORPHOLINO-TERMINATED ALKYLAMINO ETHYNYL ALANINE AMINO DIOL COMPOUNDS AS RENIN INHIBITORS | SEARLE & CO (US) | 1997-10-08 | — | — | EP | claimed |
| EP-0655062-A1 | MORPHOLINO/THIOMORPHOLINO-TERMINATED ALKYLAMINO ETHYNYL ALANINE AMINO DIOL COMPOUNDS AS RENIN INHIBITORS. | SEARLE & CO (US) | 1995-05-31 | — | — | EP | claimed |
| WO-1994004518-A1 | MORPHOLINO/THIOMORPHOLINO-TERMINATED ALKYLAMINO ETHYNYL ALANINE AMINO DIOL COMPOUNDS AS RENIN INHIBITORS | G.D. SEARLE & CO. (US) | 1994-03-03 | — | — | WO | claimed |