Anandamide

Anandamide

SCHEMBL4109856

CCCCCC=CCC=CCC=CC/C=C\CCCC(=O)NCCO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 7/20 1.00
ALDH1A1 P00352 3/20 1.00
CNR2 P34972 3/20 1.00
MEN1 O00255 2/20 1.00
BLM P54132 2/20 1.00
KMT2A Q03164 2/20 1.00
TRPV1 Q8NER1 2/20 1.00
TRPM8 Q7Z2W7 1/20 1.00
FAAH O00519 1/20 1.00
KCNK3 O14649 1/20 1.00
HPGD P15428 2/20 0.91
MAPT P10636 1/20 0.91
ALOX12 P18054 1/20 0.91
TDP1 Q9NUW8 1/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anandamide SCHEMBL13100719 1.00 CNR1 (1.00) CNR1ALDH1A1CNR2MEN1BLM
Anandamide SCHEMBL7140616 1.00 CNR1 (1.00) CNR1ALDH1A1CNR2MEN1BLM
Anandamide SCHEMBL43143 1.00 CNR1 (1.00) CNR1ALDH1A1CNR2MEN1BLM
Anandamide SCHEMBL43144 1.00 CNR1 (1.00) CNR1ALDH1A1CNR2MEN1BLM
SCHEMBL15364953 0.98 CNR1 (0.97) CNR1ALDH1A1CNR2MEN1BLM
SCHEMBL29512269 0.98 CNR1 (0.97) CNR1ALDH1A1CNR2MEN1BLM
Anandamide SCHEMBL27412236 0.98 CNR1 (0.97) CNR1ALDH1A1CNR2MEN1BLM
SCHEMBL4539275 0.98 CNR1 (0.97) CNR1ALDH1A1CNR2MEN1BLM
SCHEMBL14700549 0.98 CNR1 (0.97) CNR1ALDH1A1CNR2MEN1BLM
SCHEMBL14864037 0.98 CNR1 (0.97) CNR1ALDH1A1CNR2MEN1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043040-A Arachidonic acid ethanolamine cyclodextrin inclusion complex carrier 西泽普研究与发展有限责任公司 2024-05-14 CN disclosed
US-20090043129-A1 POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS UNIVERSITA DEGLI STUDI DI SIENA (IT) 2009-02-12 US disclosed
EP-1846364-A1 NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS Universita' Degli Studi di Siena (IT) 2007-10-24 EP disclosed
WO-2006080040-A1 NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS UNIVERSITÀ DEGLI STUDI DI SIENA (IT) 2006-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043129-A1 POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS CNR2, CNR1, GPR18 CNR1 2/4885ALDH1A1 4632/4885CNR2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.