SCHEMBL4110192

SCHEMBL4110192

Cn1nnc(C[C@@H](n2c(=O)n(CCC(C)(C)O)c3ccccc32)C(C)(C)C)n1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.44
CNR1 P21554 3/20 0.44
SLC6A2 P23975 3/20 0.33
BCL6 P41182 7/20 0.33
SLC6A4 P31645 2/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
NCOR2 Q9Y618 2/20 0.31
HTR4 Q13639 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL761489 0.80 CNR2 (0.60) CNR2CNR1
SCHEMBL30745333 0.74 CNR2 (0.56) CNR2CNR1BCL6NPC1GAA
SCHEMBL739986 0.72 CNR2 (0.73) CNR2CNR1NPC1
SCHEMBL30904706 0.70 CNR1 (0.53) CNR2CNR1BCL6NPC1GAA
SCHEMBL31357282 0.69 CNR2 (0.52) CNR2CNR1BCL6NPC1GAA
SCHEMBL20569640 0.66 CNR2 (0.51) CNR2CNR1NPC1GAA
SCHEMBL762192 0.64 CNR2 (0.63) CNR2CNR1
SCHEMBL762197 0.63 CNR2 (0.69) CNR2CNR1
SCHEMBL740426 0.63 CNR2 (0.72) CNR2CNR1
SCHEMBL739509 0.62 CNR2 (0.71) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090181957-A1 BENZIMIDAZOLONE DERIVATIVES AS CB2 RECEPTOR LIGANDS ANDO KAZUO 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181957-A1 BENZIMIDAZOLONE DERIVATIVES AS CB2 RECEPTOR LIGANDS TRPV1, CNR1, CNR2 CNR2 3/4885CNR1 2/4885SLC6A2 3649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.