Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745333 | 0.89 | CNR2 (0.56) | CNR2CNR1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL31357282 | 0.83 | CNR2 (0.52) | CNR2CNR1ALDH1A1NPC1GAA | |
| SCHEMBL30904706 | 0.81 | CNR1 (0.53) | CNR2CNR1POLBALDH1A1CYP1A2 | |
| SCHEMBL13354930 | 0.78 | CYP1A2 (0.56) | CNR2POLBALDH1A1CYP1A2NPC1 | |
| SCHEMBL12933336 | 0.73 | TOP2A (0.51) | CNR2ALDH1A1TOP2AHDAC1HTR6 | |
| SCHEMBL13322672 | 0.73 | CNR2 (0.47) | CNR2POLBALDH1A1CYP1A2TOP2A | |
| SCHEMBL22700957 | 0.73 | NPC1 (0.47) | CNR2CNR1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL20569856 | 0.72 | KDM4E (0.58) | CNR2CNR1ALDH1A1GAA | |
| SCHEMBL1128490 | 0.71 | FABP4 (0.50) | CNR2CNR1ALDH1A1CYP1A2HDAC1 | |
| SCHEMBL8347752 | 0.71 | MAPK8 (0.55) | CNR2ALDH1A1TOP2AHDAC1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630291-A1 | BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 | Cancer Research Technology Limited (GB) | 2020-04-08 | — | — | EP | claimed |
| WO-2018215801-A1 | BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-11-29 | — | — | WO | claimed |