Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL28938738 | 0.97 | — | — | |
| Tetrahydrofuran SCHEMBL29016373 | 0.90 | — | — | |
| Tetrahydrofuran SCHEMBL3618483 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TTRTSHR | |
| Tetrahydrofuran SCHEMBL1366641 | 0.82 | — | — | |
| Tetrahydrofuran SCHEMBL11521890 | 0.82 | — | — | |
| Tetrahydrofuran SCHEMBL27945552 | 0.79 | ALDH1A1 (0.44) | ALDH1A1 | |
| Tetrahydrofuran SCHEMBL28820736 | 0.79 | — | — | |
| Tetrahydrofuran SCHEMBL25298377 | 0.78 | — | — | |
| Tetrahydrofuran SCHEMBL3782865 | 0.78 | — | — | |
| Tetrahydrofuran SCHEMBL27823038 | 0.78 | ALDH1A1 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499631-A | Preparation method of olprinone hydrochloride key intermediate | 山东美泰医药有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-118126021-A | Synthesis method of ipratropium hydrochloride | 杭州科巢生物科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-116253627-A | Method for synthesizing 2-bromo-6-hydroxybenzaldehyde | 大连双硼医药化工有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-114605240-B | Preparation method of esketamine hydrochloride synthesis intermediate | 宜昌人福药业有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115448971-A | Intermediate for preparing fulvestrant and preparation method thereof | 上海弼领生物技术有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-111499631-B | Preparation method of olprinone hydrochloride key intermediate 1-imidazo [1,2-a ] pyridin-6-yl-2-acetone | 济南康桥医药科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-109020980-B | Pyrazolopyrimidine dinitrogen derivative with anti-tumor effect | 华东师范大学 | 2020-11-20 | — | — | CN | disclosed |
| CN-111499631-A | Preparation method of olprinone hydrochloride key intermediate | 山东美泰医药有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-110003276-A | A kind of double phosphine oxidization deriving species electroluminescent organic materials of thienopyrazine and the preparation method and application thereof | 中节能万润股份有限公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-104672220-B | The activator of peroxisome proliferator-activated receptor | 日本化学医药株式会社 | 2017-09-22 | — | — | CN | disclosed |
| CN-105237533-B | Tetrahydropyridine [4,3-d] miazines Hsp90 inhibitor and medical application thereof | 中国药科大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-105238415-A | Liquid crystal compound containing tetrahydropyran difluoro methylene oxygen group and preparation method and application thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD | 2016-01-13 | — | — | CN | disclosed |
| CN-105237533-A | Tetrahydropyridine [4,3-d] miazines Hsp90 inhibitor and medical application thereof | UNIV CHINA PHARMA | 2016-01-13 | — | — | CN | disclosed |
| CN-104672220-A | Activating agent for peroxisome proliferator activated receptor | NIPPON CHEMIPHAR CO | 2015-06-03 | — | — | CN | disclosed |
| CN-102083810-B | Activator of peroxisome proliferator activated receptor | NIPPON CHEMIPHAR CO.,LTD. (JP) | 2014-10-29 | — | — | CN | disclosed |
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1939205-A1 | TRICYCLIC COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | FDFT1, COASY, HMGCR | ALDH1A1 1587/4885TTR 2423/4885TSHR 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.