Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 7/20 | 0.61 |
| ▸ | IDO1 | P14902 | 5/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | SNCA | P37840 | 2/20 | 0.61 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.61 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.61 |
| ▸ | AKT1 | P31749 | 1/20 | 0.61 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.61 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.61 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.61 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthoquinone SCHEMBL28159949 | 0.84 | CDC25B (0.70) | CDC25BIDO1MAOAMAOBSNCA | |
| Naphthoquinone SCHEMBL8064673 | 0.84 | CDC25B (0.70) | CDC25BIDO1MAOAMAOBSNCA | |
| Naphthoquinone SCHEMBL27995889 | 0.81 | CDC25B (0.82) | CDC25BIDO1MAOAMAOBSNCA | |
| Naphthoquinone SCHEMBL4116599 | 0.80 | CDC25B (0.64) | CDC25BIDO1MAOAMAOBSNCA | |
| Naphthoquinone SCHEMBL28356747 | 0.80 | CDC25B (0.47) | CDC25BIDO1MAOAMAOBSNCA | |
| Naphthoquinone SCHEMBL11359780 | 0.78 | IDO1 (1.00) | CDC25BIDO1MAOAMAOBSNCA | |
| Naphthoquinone SCHEMBL42139 | 0.78 | IDO1 (1.00) | CDC25BIDO1MAOAMAOBSNCA | |
| Naphthoquinone SCHEMBL29354680 | 0.78 | IDO1 (1.00) | CDC25BIDO1MAOAMAOBSNCA | |
| Naphthoquinone SCHEMBL8861335 | 0.78 | IDO1 (1.00) | CDC25BIDO1MAOAMAOBSNCA | |
| Naphthoquinone SCHEMBL28565535 | 0.77 | IDO1 (0.58) | CDC25BIDO1MAOAMAOBSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247472-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | FLUOFARMA (FR) | 2009-10-01 | — | — | US | disclosed |
| EP-2010481-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | Fluofarma (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007125196-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | FLUOFARMA (FR) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247472-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | CCNA1, MKI67, CCNT1 | CDC25B 90/4885IDO1 1244/4885MAOA 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.