SCHEMBL411154

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL412666	0.89	IDO1 (0.45)	ALDH1A1LMNAKDM4EHPGDMAPK1
	SCHEMBL411571	0.87	KMT2A (0.44)	ALDH1A1LMNAKDM4EHPGDMAPK1
	SCHEMBL413452	0.87	SMPD3 (0.41)	ALDH1A1KDM4EHPGDMEN1KMT2A
	SCHEMBL413153	0.86	PDGFRB (0.42)	ALDH1A1LMNAKDM4EHPGDMAPK1
	SCHEMBL14847368	0.86	CHEK1 (0.49)	ALDH1A1LMNAPOLBCHEK1GAA
	SCHEMBL408075	0.86	PDE10A (0.42)	ALDH1A1LMNAKDM4EMAPK1MEN1
	SCHEMBL407088	0.86	CHEK1 (0.49)	ALDH1A1KDM4ESMN1; SMN2MAPTGSK3B
	SCHEMBL412144	0.85	KDM4E (0.45)	ALDH1A1KDM4EHPGDMAPK1MEN1
	SCHEMBL411959	0.83	CHEK1 (0.40)	ALDH1A1LMNAMAPTCHEK1
	SCHEMBL412152	0.83	PDGFRB (0.44)	ALDH1A1KDM4EHPGDMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.