Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.57 |
| ▸ | PTGIR | P43119 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | PTGFR | P43088 | 2/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4111896 | 1.00 | PTGER4 (0.57) | PTGER4PTGER2PTGIRTSHRPTGFR | |
| SCHEMBL4112689 | 0.88 | ALDH1A1 (0.57) | PTGER4PTGER2PTGIRTSHRPTGFR | |
| SCHEMBL4112690 | 0.88 | ALDH1A1 (0.57) | PTGER4PTGER2PTGIRTSHRPTGFR | |
| SCHEMBL13845738 | 0.88 | PTGIR (0.42) | PTGER4PTGER2PTGIRTSHRPTGFR | |
| SCHEMBL3992485 | 0.85 | PTGFR (0.55) | PTGER4TSHRPTGFRPTGER3HPGD | |
| SCHEMBL3992489 | 0.85 | PTGFR (0.55) | PTGER4TSHRPTGFRPTGER3HPGD | |
| SCHEMBL4100854 | 0.83 | MAPT (0.41) | PTGER4PTGER2PTGIRTSHRPTGFR | |
| SCHEMBL4100856 | 0.83 | MAPT (0.41) | PTGER4PTGER2PTGIRTSHRPTGFR | |
| SCHEMBL4192872 | 0.83 | ALDH1A1 (0.46) | PTGER4PTGER2PTGIRTSHRPTGFR | |
| SCHEMBL4192876 | 0.83 | ALDH1A1 (0.46) | PTGER4PTGER2PTGIRTSHRPTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009065081-A2 | PROSTAGLANDIN E1 AND E2 ANALOGS FOR THE TREATMENT OF VARIOUS MEDICAL CONDITIONS | CAYMAN CHEMICAL COMPANY (US) | 2009-05-22 | — | — | WO | disclosed |
| US-20090124695-A1 | PROSTAGLANDIN E1 AND E2 ANALOGS FOR THE TREATMENT OF VARIOUS MEDICAL CONDITIONS | CAYMAN CHEMICAL COMPANY (US) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124695-A1 | PROSTAGLANDIN E1 AND E2 ANALOGS FOR THE TREATMENT OF VARIOUS MEDICAL CONDITIONS | PTGER1, PTGER4, PTGER2 | PTGER4 2/4885PTGER2 3/4885PTGIR 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.