Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669246 | 0.84 | MCL1 (0.62) | MEN1KMT2AL3MBTL1LMNATP53 | |
| SCHEMBL7047250 | 0.84 | F10 (0.59) | MEN1KMT2AL3MBTL1TP53ALDH1A1 | |
| SCHEMBL13753351 | 0.84 | MCL1 (0.61) | MEN1KMT2AL3MBTL1LMNATP53 | |
| SCHEMBL30174163 | 0.82 | HDAC1 (0.66) | MEN1KMT2AL3MBTL1RXFP1MCL1 | |
| SCHEMBL30174165 | 0.82 | HDAC1 (0.66) | MEN1KMT2AL3MBTL1RXFP1MCL1 | |
| SCHEMBL3551679 | 0.82 | HDAC1 (0.66) | MEN1KMT2AL3MBTL1RXFP1MCL1 | |
| SCHEMBL19308452 | 0.81 | HDAC1 (0.65) | MEN1KMT2AL3MBTL1LMNATP53 | |
| SCHEMBL30525414 | 0.80 | MCL1 (0.65) | MEN1KMT2AL3MBTL1MCL1RAB9A | |
| SCHEMBL31162122 | 0.80 | MEN1 (0.52) | MEN1KMT2AL3MBTL1LMNATP53 | |
| SCHEMBL31162124 | 0.80 | MEN1 (0.52) | MEN1KMT2AL3MBTL1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284963-B1 | NOVEL CALCIUM RECEPTOR ACTIVE MOLECULES AND METHOD FOR PREPARING SAME | CENTRE NAT RECH SCIENT (FR) | 2012-05-09 | — | — | EP | disclosed |