Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222267 | 1.00 | HSD11B1 (0.71) | HSD11B1HSD11B2 | |
| SCHEMBL12884724 | 0.91 | HSD11B1 (0.59) | HSD11B1HSD11B2 | |
| SCHEMBL1223443 | 0.89 | HSD11B1 (0.59) | HSD11B1HSD11B2 | |
| SCHEMBL1223221 | 0.89 | HSD11B1 (0.56) | HSD11B1HSD11B2 | |
| SCHEMBL1222997 | 0.89 | HSD11B1 (0.58) | HSD11B1HSD11B2 | |
| SCHEMBL1222532 | 0.89 | HSD11B1 (0.73) | HSD11B1HSD11B2 | |
| SCHEMBL1223204 | 0.88 | HSD11B1 (0.58) | HSD11B1HSD11B2 | |
| SCHEMBL1222106 | 0.87 | HSD11B1 (0.73) | HSD11B1HSD11B2 | |
| SCHEMBL14293699 | 0.85 | HSD11B1 (0.56) | HSD11B1HSD11B2 | |
| SCHEMBL1222070 | 0.85 | HSD11B1 (0.72) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064187-A2 | INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | Vitae Pharmaceuticals, Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008024497-A2 | INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE TYPE 1 | VITAE PHARMACEUTICALS, INC. (US) | 2008-02-28 | — | — | WO | disclosed |