Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methyl Salicylate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Salicylate SCHEMBL27586961 | 0.94 | LMNA (0.88) | LMNATSHRALDH1A1KMT2AHTT | |
| Methyl Salicylate SCHEMBL27760219 | 0.93 | LMNA (0.79) | LMNATSHRALDH1A1KMT2AHTT | |
| Methyl Salicylate SCHEMBL27571018 | 0.92 | LMNA (0.85) | LMNATSHRALDH1A1KMT2AHTT | |
| Methyl Salicylate SCHEMBL29370254 | 0.92 | LMNA (1.00) | LMNATSHRALDH1A1KMT2AHTT | |
| Methyl Salicylate SCHEMBL1872042 | 0.92 | LMNA (1.00) | LMNATSHRALDH1A1KMT2AHTT | |
| Methyl Salicylate SCHEMBL5312 | 0.92 | LMNA (1.00) | LMNATSHRALDH1A1KMT2AHTT | |
| Methyl Salicylate SCHEMBL28031266 | 0.91 | LMNA (0.81) | LMNATSHRALDH1A1KMT2AHTT | |
| Methyl Salicylate SCHEMBL23045204 | 0.90 | LMNA (0.96) | LMNATSHRALDH1A1KMT2AHTT | |
| Methyl Salicylate SCHEMBL5795853 | 0.90 | LMNA (0.96) | LMNATSHRALDH1A1KMT2AHTT | |
| Methyl Salicylate SCHEMBL7961798 | 0.90 | LMNA (0.96) | LMNATSHRALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106135277-A | A kind of compositions preventing and treating rice stinkbug silk worm and preparation method thereof | 赵思璐 | 2016-11-23 | — | — | CN | claimed |
| CN-106106527-A | A kind of compositions preventing and treating Atrijuglans hetaohei and preparation method thereof | 叶松 | 2016-11-16 | — | — | CN | claimed |
| CN-106070318-A | A kind of compositions preventing and treating Chinese cabbage downy mildew and preparation method thereof | 刘园 | 2016-11-09 | — | — | CN | claimed |
| CN-106070277-A | A kind of compositions preventing and treating Oeobia undalis and preparation method thereof | 刘园 | 2016-11-09 | — | — | CN | claimed |
| CN-106035372-A | Composition for preventing and controlling wheat blossom midges and preparation method thereof | 淄博夸克医药技术有限公司 | 2016-10-26 | — | — | CN | claimed |
| CN-105994279-A | Composition for preventing and treating phytomyza horticola goureau and preparing method thereof | 叶松 | 2016-10-12 | — | — | CN | claimed |
| CN-105994351-A | Composition for preventing and treating Echinocnemus sguameus and preparation method thereof | 刘园 | 2016-10-12 | — | — | CN | claimed |
| CN-1853712-A | External-use breast mask for treating facial nerve paralysis and preparation method thereof | SHAO JIANGUO (CN) | 2006-11-01 | — | — | CN | claimed |
| US-5830380-A | Methyl salicylate antifreeze solution method | CAMCO MANUFACTURING, INC. (US) | 1998-11-03 | — | — | US | claimed |
| WO-2024036600-A1 | AUTONOMOUS PARTHENOGENETIC HAPLOID REPRODUCTION METHOD FOR MATERNAL CELLS AND USE THEREOF IN BREEDING | 中国农业科学院作物科学研究所 | 2024-02-22 | — | — | WO | disclosed |
| US-11788100-B2 | Gene for induction of parthenogenesis, a component of apomictic reproduction | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230089653-A1 | GENE FOR INDUCTION OF PARTHENOGENESIS, A COMPONENT OF APOMICTIC REPRODUCTION | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2023-03-23 | — | — | US | disclosed |
| CN-115786390-A | Maternal cell autonomous parthenogenetic haploid reproduction method and breeding application thereof | 中国农业科学院作物科学研究所 | 2023-03-14 | — | — | CN | disclosed |
| US-20210340559-A1 | GENE FOR INDUCTION OF PARTHENOGENESIS, A COMPONENT OF APOMICTIC REPRODUCTION | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2021-11-04 | — | — | US | disclosed |
| WO-2009073190-A1 | FAST DISSOLVING FILMS AND COATINGS FOR CONTROLLED RELEASE OF FLAVORS, ACTIVE PHARMACEUTICAL INGREDIENTS, FOOD SUBSTANCES, AND NICOTINE | SWEDISH MATCH NORTH AMERICA, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| US-7470738-B2 | Non-aqueous absorbent and use thereof | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2008-12-30 | — | — | US | disclosed |
| CN-101081300-A | Long-acting anti-parasite medicine injection | QINGDAO CONTINENT INDUSTRY CO (CN) | 2007-12-05 | — | — | CN | disclosed |
| US-20050136247-A1 | Non-aqueous absorbent and use thereof | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-23 | — | — | US | disclosed |
| US-5830380-A | Methyl salicylate antifreeze solution method | CAMCO MANUFACTURING, INC. (US) | 1998-11-03 | — | — | US | disclosed |
| WO-1998011867-A1 | ORAL COMPOSITIONS CONTAINING A ZINC COMPOUND | WARNER-LAMBERT COMPANY (US) | 1998-03-26 | — | — | WO | disclosed |