Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 14/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | TAS2R8 | Q9NYW2 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3528116 | 0.99 | IGF1R (0.39) | IGF1RAURKATAS2R8AR | |
| SCHEMBL13254917 | 0.92 | TAS2R8 (0.38) | IGF1RTAS2R8 | |
| Trifluoroacetic Acid SCHEMBL3525656 | 0.90 | IGF1R (0.38) | IGF1RAURKATAS2R8AR | |
| SCHEMBL3527116 | 0.82 | AR (0.54) | TAS2R8AR | |
| SCHEMBL3528563 | 0.82 | AR (0.46) | AR | |
| SCHEMBL1973106 | 0.80 | IGF1R (0.41) | IGF1RAURKATAS2R8 | |
| SCHEMBL3526742 | 0.79 | IGF1R (0.43) | IGF1RTAS2R8AR | |
| SCHEMBL3525161 | 0.79 | AR (0.41) | AR | |
| SCHEMBL3525538 | 0.79 | AR (0.53) | AR | |
| SCHEMBL3530989 | 0.78 | AR (0.40) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061767-B1 | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use | SANOFI SA (FR) | 2014-12-17 | — | — | EP | disclosed |
| EP-2061767-A1 | ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE | Sanofi-Aventis (FR) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008017381-A1 | ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE | SANOFI-AVENTIS (FR) | 2008-02-14 | — | — | WO | disclosed |