Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | FASN | P49327 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL14908944 | 0.98 | DPP4 (0.32) | MMEFASNPDE7ADPP4 | |
| SCHEMBL27903631 | 0.97 | MME (0.33) | MMEFASNPDE7ADPP4 | |
| SCHEMBL1503908 | 0.97 | MME (0.33) | MMEFASNPDE7ADPP4 | |
| Sulfuric Acid SCHEMBL17472893 | 0.91 | MME (0.31) | MMEFASN | |
| SCHEMBL20293628 | 0.86 | MME (0.34) | MMEFASNPDE7ADPP4 | |
| SCHEMBL20293481 | 0.86 | MME (0.34) | MMEFASNPDE7ADPP4 | |
| SCHEMBL31444622 | 0.86 | BTK (0.36) | — | |
| SCHEMBL20328936 | 0.84 | FASN (0.38) | MMEFASN | |
| Oxalic Acid SCHEMBL29538921 | 0.82 | BTK (0.46) | — | |
| SCHEMBL4632507 | 0.81 | MME (0.33) | MMEFASNPDE7ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024120275-A1 | PREPARATION METHOD FOR EDOXABAN AND INTERMEDIATE THEREOF | 浙江华海药业股份有限公司 | 2024-06-13 | — | — | WO | claimed |
| EP-2980090-A1 | METHOD FOR PRODUCING (1S,4S,5S)-4-BROMO-6-OXABICYCLO[3.2.1]OCTAN-7-ONE | Daiichi Sankyo Co., Ltd. (JP) | 2016-02-03 | — | — | EP | claimed |
| WO-2024120275-A1 | PREPARATION METHOD FOR EDOXABAN AND INTERMEDIATE THEREOF | 浙江华海药业股份有限公司 | 2024-06-13 | — | — | WO | disclosed |
| WO-2019004114-A1 | PRODUCTION METHOD FOR DIAMINE DERIVATIVE BY FLOW SYNTHESIS | 第一三共株式会社 | 2019-01-03 | — | — | WO | disclosed |
| EP-2602242-B1 | PROCESS FOR PREPARING COMPOUND BY NOVEL SANDMEYER-LIKE REACTION USING NITROXIDE RADICAL COMPOUND AS REACTION CATALYST | DAIICHI SANKYO CO LTD (JP) | 2017-08-23 | — | — | EP | disclosed |
| EP-2980067-B1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2017-05-17 | — | — | EP | disclosed |
| EP-2589590-B1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO CO LTD (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-9447118-B2 | Preparation method of optically active diamine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-20 | — | — | US | disclosed |
| EP-1925611-B1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| EP-2980067-A1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-02-03 | — | — | EP | disclosed |
| EP-2980090-A1 | METHOD FOR PRODUCING (1S,4S,5S)-4-BROMO-6-OXABICYCLO[3.2.1]OCTAN-7-ONE | Daiichi Sankyo Co., Ltd. (JP) | 2016-02-03 | — | — | EP | disclosed |
| EP-2407457-B1 | PROCESS FOR PRODUCING DIAMINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2015-04-22 | — | — | EP | disclosed |
| US-8901345-B2 | Process for preparation of optically active diamine derivative salt | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20130165657-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-06-27 | — | — | US | disclosed |
| EP-2602242-A1 | PROCESS FOR PREPARING COMPOUND BY NOVEL SANDMEYER-LIKE REACTION USING NITROXIDE RADICAL COMPOUND AS REACTION CATALYST | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-20130144061-A1 | PROCESS FOR PREPARING A COMPOUND BY A NOVEL SANDMEYER-LIKE REACTION USING A NITROXIDE RADICAL COMPOUND AS A REACTION CATALYST | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-06-06 | — | — | US | disclosed |
| EP-2589590-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-8357808-B2 | Process for producing diamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-22 | — | — | US | disclosed |
| US-20090105491-A1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1925611-A1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Daiichi Sankyo Company, Limited (JP) | 2008-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105491-A1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TFPI, F2, SERPINC1 | MME 912/4885FASN 2979/4885PDE7A 477/4885 |
| US-20130165657-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | TFPI, F12, TFPI2 | MME 443/4885FASN 4407/4885PDE7A 697/4885 |
| US-20130144061-A1 | PROCESS FOR PREPARING A COMPOUND BY A NOVEL SANDMEYER-LIKE REACTION USING A NITROXIDE RADICAL COMPOUND AS A REACTION CATALYST | TYR, NOX5, NOXO1 | MME 823/4885FASN 4600/4885PDE7A 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.