Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TAS2R8 | Q9NYW2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4109044 | 0.93 | AR (0.49) | ARCNR1TAS2R8 | |
| SCHEMBL3527421 | 0.88 | AR (0.49) | ARCNR1TAS2R8 | |
| SCHEMBL3529259 | 0.87 | AR (0.55) | ARCNR1TAS2R8 | |
| SCHEMBL3525366 | 0.87 | AR (0.51) | ARCNR1TAS2R8 | |
| SCHEMBL3526165 | 0.85 | AR (0.52) | ARCNR1 | |
| SCHEMBL1208074 | 0.84 | AR (0.49) | ARCNR1TAS2R8 | |
| SCHEMBL12894791 | 0.84 | AR (0.46) | ARCNR1 | |
| SCHEMBL3527116 | 0.83 | AR (0.54) | ARCNR1TAS2R8 | |
| SCHEMBL1207317 | 0.83 | AR (0.49) | ARCNR1 | |
| SCHEMBL3526170 | 0.83 | PGR (0.49) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061767-A1 | ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE | Sanofi-Aventis (FR) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008017381-A1 | ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE | SANOFI-AVENTIS (FR) | 2008-02-14 | — | — | WO | disclosed |