Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24502720 | 0.80 | TSHR (0.34) | EPHX2 | |
| SCHEMBL28176134 | 0.75 | CASP1 (0.40) | — | |
| SCHEMBL24859121 | 0.75 | CASP1 (0.40) | — | |
| SCHEMBL4097444 | 0.74 | — | — | |
| SCHEMBL375727 | 0.73 | CA12 (0.34) | EPHX2 | |
| SCHEMBL3219005 | 0.71 | EPHX2 (0.35) | EPHX2 | |
| SCHEMBL22961013 | 0.71 | CA12 (0.33) | EPHX2 | |
| SCHEMBL1567820 | 0.71 | TSHR (0.35) | EPHX2 | |
| Ammonia Solution, Strong SCHEMBL28079944 | 0.71 | CA12 (0.33) | EPHX2 | |
| SCHEMBL18402516 | 0.69 | CA12 (0.32) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058671-A1 | SUBSTITUTED QUINAZOLINE AND PYRIDO-PYRIMIDINE DERIVATIVES | ENDO PHARMACEUTICALS INC. (US) | 2012-05-03 | — | — | WO | disclosed |