Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755872 | 0.89 | USP2 (0.60) | USP2LMNACYP2C9CYP2C19TSHR | |
| SCHEMBL2092776 | 0.84 | USP2 (0.59) | USP2LMNACYP2C9CYP2C19TSHR | |
| SCHEMBL12672893 | 0.82 | USP2 (0.57) | USP2LMNACYP2C9CYP2C19TSHR | |
| SCHEMBL967320 | 0.81 | LMNA (0.70) | LMNATSHRHSD17B10MEN1KMT2A | |
| SCHEMBL19226522 | 0.80 | USP2 (0.59) | USP2LMNACYP2C9CYP2C19TSHR | |
| Hydrochloric Acid SCHEMBL27708825 | 0.80 | LMNA (0.68) | LMNATSHRHSD17B10MEN1KMT2A | |
| SCHEMBL27749182 | 0.80 | LMNA (0.49) | LMNATSHRMAPTBLMCYP1A2 | |
| SCHEMBL12783342 | 0.79 | USP2 (0.55) | USP2LMNACYP2C9CYP2C19TSHR | |
| SCHEMBL14521669 | 0.79 | LMNA (0.62) | USP2LMNACYP2C9CYP2C19TSHR | |
| SCHEMBL16565835 | 0.78 | USP2 (0.65) | USP2LMNACYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038278-A2 | THIAZOLINE AND OXAZOLINE DERIVATIVES AND THEIR METHODS OF USE | Abbott Laboratories (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008002956-A2 | THIAZOLINE AND OXAZOLINE DERIVATIVES AND THEIR METHODS OF USE | ABBOTT LABORATORIES (US) | 2008-01-03 | — | — | WO | disclosed |