SCHEMBL4118151

SCHEMBL4118151

ClC1CCC1.[MgH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14127355 0.95
SCHEMBL280288 0.95
SCHEMBL11723948 0.90 CES2 (0.33)
Fluoride SCHEMBL15271293 0.90
SCHEMBL15648230 0.90
SCHEMBL8358852 0.86 CES2 (0.39)
SCHEMBL18107290 0.86
SCHEMBL888568 0.86
SCHEMBL2479205 0.82
SCHEMBL8044474 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930381-A Synthesis method of Z-configuration chiral olefin 深圳连续制药科技有限公司 2025-05-06 CN claimed
CN-118373723-A Asymmetric alkylation reaction method of chain racemization allyl ether 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2024-07-23 CN claimed
CN-119930381-A Synthesis method of Z-configuration chiral olefin 深圳连续制药科技有限公司 2025-05-06 CN disclosed
CN-115362153-B Azaspiro compounds as monoacylglycerol lipase modulators 詹森药业有限公司 2025-01-07 CN disclosed
CN-118373723-A Asymmetric alkylation reaction method of chain racemization allyl ether 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2024-07-23 CN disclosed
EP-2770987-B1 NOVEL COMPOUNDS THAT ARE ERK INHIBITORS MERCK SHARP & DOHME (US) 2018-04-04 EP disclosed
US-9758480-B2 1-(cycloalkyl-carbonyl)proline derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2017-09-12 US disclosed
US-9718840-B2 Condensed 5-oxazolidinone derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2017-08-01 US disclosed
US-20170022218-A1 CONDENSED 5-OXAZOLIDINONE DERIVATIVE SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2017-01-26 US disclosed
EP-3095786-A1 CONDENSED 5-OXAZOLIDINONE DERIVATIVE Sumitomo Dainippon Pharma Co., Ltd. (JP) 2016-11-23 EP disclosed
CN-106103453-A It is condensed 5 oxazolidinone derivatives 大日本住友制药株式会社 2016-11-09 CN disclosed
CN-102858743-A Spiro-condensed cyclohexane derivatives as HSL inhibitors useful for the treatment of diabetes HOFFMANN LA ROCHE 2013-01-02 CN disclosed
CN-102858767-A Aminopyrimidines as SYK inhibitors MERCK SHARP & DOHME 2013-01-02 CN disclosed
CN-102741227-A Aryl benzylamine compounds NOVARTIS AG 2012-10-17 CN disclosed
CN-101195632-B Method for synthesizing cycloalkyl boric acid compound SHANGHAI CHEMPARTNER CO LTD 2011-09-14 CN disclosed
US-20090239928-A1 N-Pyrrolidin-3YL-Amide Derivatives As Serotonin and Noradrenalin Re-Uptake Inhibitors PFIZER INC. 2009-09-24 US disclosed
CN-101195632-A Method for synthesizing cycloalkyl boric acid compound SHANGHAI RUIZHI CHEMICAL STUDY (CN) 2008-06-11 CN disclosed
EP-1828121-A2 N-PYRROLIDIN-3-YL-AMIDE DERIVATIVES AS SEROTONIN AND NORADRENALIN RE-UPTAKE INHIBITORS Pfizer Limited (GB) 2007-09-05 EP disclosed
WO-2006064336-A2 N-PYRROLIDIN-3-YL-AMIDE DERIVATIVES AS SEROTONIN AND NORADRENALIN RE-UPTAKE INHIBITORS PFIZER LIMITED (GB) 2006-06-22 WO disclosed
US-H2060-H1 Cyclobutyl silanes for catalysts useful for making highly isotactic olefin polymers ENGELHARD CORPORATION 2003-03-04 US disclosed