Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369004 | 1.00 | MAPT (0.61) | MAPTSMN1; SMN2HTTDNM1KDM4E | |
| Sulfamide SCHEMBL11870110 | 0.89 | MAPT (0.51) | MAPTSMN1; SMN2HTTDNM1KDM4E | |
| SCHEMBL7277860 | 0.89 | MAPT (0.68) | MAPTSMN1; SMN2HTTDNM1KDM4E | |
| SCHEMBL1298434 | 0.83 | MAPT (0.61) | MAPTSMN1; SMN2HTTDNM1KDM4E | |
| SCHEMBL11427950 | 0.81 | BCHE (0.48) | MAPTSMN1; SMN2HTTDNM1MEN1 | |
| SCHEMBL13838308 | 0.81 | MAPT (0.59) | MAPTSMN1; SMN2HTTDNM1KDM4E | |
| SCHEMBL11154614 | 0.81 | MAPT (0.59) | MAPTSMN1; SMN2HTTDNM1KDM4E | |
| SCHEMBL5423470 | 0.81 | MAPT (0.65) | MAPTSMN1; SMN2HTTDNM1KDM4E | |
| SCHEMBL168120 | 0.79 | MAPT (0.57) | MAPTSMN1; SMN2HTTDNM1KDM4E | |
| SCHEMBL7346554 | 0.79 | MAPT (0.58) | MAPTSMN1; SMN2HTTDNM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10218866-A | — | — | None | — | — | JP | disclosed |
| JP-11005786-A | — | — | None | — | — | JP | disclosed |
| JP-9278722-A | — | — | None | — | — | JP | disclosed |
| CN-109762853-B | Method for synthesizing isopropanol beta-alkamine derivative on line by lipase catalysis | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| US-10183011-B2 | Anti-depression compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-01-22 | — | — | US | disclosed |
| US-10183011-B2 | Anti-depression compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-01-22 | — | — | US | disclosed |
| US-20180318255-A1 | Pro-Neurogenic Compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2018-11-08 | — | — | US | disclosed |
| CN-108329253-A | Preceding neurogenic compounds | 得克萨斯州大学系统董事会 | 2018-07-27 | — | — | CN | disclosed |
| US-20180127367-A1 | Pro-Neurogenic Compounds | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2018-05-10 | — | — | US | disclosed |
| US-20180127367-A1 | Pro-Neurogenic Compounds | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2018-05-10 | — | — | US | disclosed |
| US-20120022096-A1 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2012006419-A2 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012006419-A2 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-01-12 | — | — | WO | disclosed |
| JP-H115786-A | NOVEL AMINOHYDROXYPROPYLPIPERAZINE DERIVATIVE | POLA CHEM IND INC | 1999-01-12 | — | — | JP | disclosed |
| JP-H10218866-A | AGENT FOR INHIBITING REUPTAKE OF DOPAMINE | POLA CHEM IND INC | 1998-08-18 | — | — | JP | disclosed |
| JP-H09278722-A | OPTICALLY ACTIVE PROPANOL DERIVATIVE | POLA CHEM IND INC | 1997-10-28 | — | — | JP | disclosed |
| US-4215220-A | 1-(2-Oxysubstituted-3-anilinopropyl)-imidazoles | CILAG-CHEMIE A.G. (CH) | 1980-07-29 | — | — | US | disclosed |
| US-4060544-A | COUPLERS | GAF CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4039524-A | Keto-amido containing phenylazo benzothiazole dyestuffs | GAF CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |
| US-3931145-A | POLYESTER | GAF CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022096-A1 | PRO-NEUROGENIC COMPOUNDS | BDNF, GAP43, DCX | MAPT 136/4885SMN1; SMN2 50/4885HTT 31/4885 |
| US-20180127367-A1 | Pro-Neurogenic Compounds | BDNF, GAP43, DCX | MAPT 136/4885SMN1; SMN2 50/4885HTT 31/4885 |
| US-20180318255-A1 | Pro-Neurogenic Compounds | BDNF, GAP43, DCX | MAPT 136/4885SMN1; SMN2 50/4885HTT 31/4885 |
| US-10183011-B2 | Anti-depression compounds | BDNF, DCX, GAP43 | MAPT 142/4885SMN1; SMN2 63/4885HTT 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.