SCHEMBL4120686

SCHEMBL4120686

O=C(O)/C=C/C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10500212 1.00
SCHEMBL1903917 1.00
Fumaric Acid SCHEMBL342742 0.84
Maleic Acid SCHEMBL532168 0.84
Fumaric Acid SCHEMBL342743 0.84
Fumaric Acid SCHEMBL2138822 0.84 TSHR (0.90)
Fumaric Acid SCHEMBL2139580 0.84 TSHR (0.90)
SCHEMBL244945 0.84
SCHEMBL244944 0.84
SCHEMBL258961 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3080610-A1 UNIVERSAL ANTIGEN RETRIEVAL COMPOUNDS AND METHODS OF USE University of Houston System (US) 2016-10-19 EP claimed
WO-2015088667-A1 UNIVERSAL ANTIGEN RETRIEVAL COMPOUNDS AND METHODS OF USE UNIVERSITY OF HOUSTON SYSTEM (US) 2015-06-18 WO claimed
US-20150168417-A1 Universal Antigen Retrieval Compounds and Methods of Use UNIVERSITY OF HOUSTON SYSTEM (US) 2015-06-18 US claimed
CN-101914171-B Sulfonic acid ultraviolet (UV)-cured aqueous epoxy emulsion and preparation method thereof UNIV SOUTH CHINA TECH 2012-02-08 CN claimed
CN-101914171-A Sulfonic acid ultraviolet (UV)-cured aqueous epoxy emulsion and preparation method thereof UNIV SOUTH CHINA TECH 2010-12-15 CN claimed
EP-3315968-B1 UNIVERSAL ANTIGEN RETRIEVAL COMPOUNDS AND METHODS OF USE UNIV HOUSTON SYSTEM (US) 2025-10-15 EP disclosed
US-12037354-B2 Cyclic pantetheine derivatives and uses thereof VECTIVBIO COMET AG (CH) 2024-07-16 US disclosed
US-12017997-B2 Host-targeted pan-respiratory antiviral small molecule therapeutics PROSETTA BIOSCIENCES, INC. (US) 2024-06-25 US disclosed
US-20240190826-A1 Novel Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics PROSETTA BIOSCIENCES, INC. 2024-06-13 US disclosed
CN-117586256-A Substituted heterocyclic compounds 首药控股(北京)股份有限公司 2024-02-23 CN disclosed
EP-4313067-A1 TREATMENT OF IMMUNE-RELATED DISORDERS, KIDNEY DISORDERS, LIVER DISORDERS, HEMOLYTIC DISORDERS, AND OXIDATIVE STRESS-ASSOCIATED DISORDERS USING NRH, NARH AND REDUCED DERIVATIVES THEREOF Mitopower LLC (US) 2024-02-07 EP disclosed
WO-2024006445-A1 METHODS FOR TREATMENT OF CANCER FRONTIER MEDICINES CORPORATION (US) 2024-01-04 WO disclosed
EP-1939205-A1 TRICYCLIC COMPOUND Daiichi Sankyo Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007071085-A1 IMPROVEMENTS IN OR RELATED TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2007-06-28 WO disclosed
US-20070129348-A1 Receptor antagonist TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-06-07 US disclosed
US-20060199795-A1 Receptor agonists TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-09-07 US disclosed
EP-1623710-A1 RECEPTOR ANTAGONIST Takeda Pharmaceutical Company Limited (JP) 2006-02-08 EP disclosed
EP-1591120-A1 RECEPTOR AGONISTS Takeda Chemical Industries, Ltd. (JP) 2005-11-02 EP disclosed
WO-1992000972-A1 RENIN INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1992-01-23 WO disclosed
US-4551277-A 4-(3-Acylamino-2-oxo-1-azetidinyl)-4-oxo-2-butenoic acid E. R. SQUIBB & SONS, INC. (US) 1985-11-05 US disclosed