Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL5191636 | 1.00 | TDP1 (0.59) | TDP1TSHRALDH1A1THRBLMNA | |
| Propylene Glycol SCHEMBL17272918 | 1.00 | TDP1 (0.59) | TDP1TSHRALDH1A1THRBLMNA | |
| Propylene Glycol SCHEMBL159902 | 0.94 | — | — | |
| Propylene Glycol SCHEMBL2026277 | 0.94 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL8145561 | 0.94 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL4596786 | 0.94 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL21060833 | 0.92 | TDP1 (0.50) | TDP1TSHR | |
| Propylene Glycol SCHEMBL11859164 | 0.91 | TDP1 (0.62) | TDP1TSHRALDH1A1LMNA | |
| Glycerin SCHEMBL18832286 | 0.90 | TDP1 (0.48) | TDP1TSHRALDH1A1THRBLMNA | |
| Propylene Glycol SCHEMBL27598741 | 0.88 | TDP1 (0.59) | TDP1TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926503-B1 | COMPOSITION AND METHOD FOR DEACTIVATING ALLERGENIC PROTEINS ON SURFACES | STEPAN CO (US) | 2011-08-24 | — | — | EP | claimed |
| EP-1971677-A1 | SOAP COMPOSITION WITH ENCAPSULATES | Colgate-Palmolive Company (US) | 2008-09-24 | — | — | EP | claimed |
| WO-2007073565-A1 | SOAP COMPOSITION WITH ENCAPSULATES | COLGATE-PALMOLIVE COMPANY (US) | 2007-06-28 | — | — | WO | claimed |
| US-20070142264-A1 | Odor elimination composition for use on soft surfaces | S.C. JOHNSON & SON, INC. (US) | 2007-06-21 | — | — | US | claimed |
| EP-1495087-A1 | WATER-ACTIVATED, EXOTHERMIC CHEMICAL DEICING FORMULATIONS | MICHIGAN STATE UNIVERSITY (US) | 2005-01-12 | — | — | EP | claimed |
| WO-2003089539-A1 | WATER-ACTIVATED, EXOTHERMIC CHEMICAL DEICING FORMULATIONS | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | claimed |
| US-6623657-B1 | Succinic acid and/or succinic anhydride and neutralizing base; does not damage aircraft alloys or concrete runways | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-09-23 | — | — | US | claimed |
| US-5703025-A | MELT BLEND OF SOAP, SURFACTANT AND SOLVENT | THE PROCTER & GAMBLE COMPANY (US) | 1997-12-30 | — | — | US | claimed |
| EP-0775195-A1 | PROCESS FOR MAKING A TRANSPARENT PERSONAL CLEANSING BAR | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-28 | — | — | EP | claimed |
| EP-0775194-A1 | TRANSPARENT PERSONAL CLEANSING BAR | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-28 | — | — | EP | claimed |
| WO-1996004360-A1 | TRANSPARENT PERSONAL CLEANSING BAR | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-15 | — | — | WO | claimed |
| WO-1996004361-A1 | PROCESS FOR MAKING A TRANSPARENT PERSONAL CLEANSING BAR | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-15 | — | — | WO | claimed |
| WO-1994025517-A1 | CURED UNSATURATED POLYESTERS GLYCOLYSIS FOR RECYCLE REACTANT | ASHLAND OIL, INC. (US) | 1994-11-10 | — | — | WO | claimed |
| EP-0542181-A1 | Cast primer and small-diameter explosive composition | IRECO INCORPORATED (US) | 1993-05-19 | — | — | EP | claimed |
| CN-117888226-A | Preparation method of degradable regenerated fibers and plush toy | 苏州亲泰儿玩具有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-11938213-B2 | Hair cosmetic compositions containing cationic polymers, acrylate-based polymers, gums, and polyols | L'OREAL (FR) | 2024-03-26 | — | — | US | disclosed |
| EP-3517596-B1 | METHOD OF MAKING AN OPAQUE LIQUID DETERGENT COMPOSITION | PROCTER & GAMBLE (US) | 2024-03-20 | — | — | EP | disclosed |
| US-3972873-A | Certain pyrido[3,2-e]1,4-diazepinones and derivatives | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-08-03 | — | — | US | disclosed |
| US-3956491-A | ANTIULCER AGENTS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-05-11 | — | — | US | disclosed |
| US-3941775-A | 6-Aza-3H-1,4-benzodiazepines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-03-02 | — | — | US | disclosed |