Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL2026277 | 1.00 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNAAKR1B1 | |
| Propylene Glycol SCHEMBL159902 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL8145561 | 1.00 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNAAKR1B1 | |
| Propylene Glycol SCHEMBL11859164 | 0.97 | TDP1 (0.62) | TDP1TSHRALDH1A1LMNAAKR1B1 | |
| Propylene Glycol SCHEMBL5191636 | 0.94 | TDP1 (0.59) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL412140 | 0.94 | TDP1 (0.59) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL27598741 | 0.94 | TDP1 (0.59) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL17272918 | 0.94 | TDP1 (0.59) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL18064606 | 0.91 | TDP1 (0.56) | TDP1TSHRALDH1A1 | |
| Propylene Glycol SCHEMBL27686921 | 0.89 | TDP1 (0.53) | TDP1TSHRALDH1A1LMNAAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434625-B1 | ENHANCED FORMULATIONS FOR NEUTRALIZATION OF CHEMICAL, BIOLOGICAL AND INDUSTRIAL TOXANTS | NAT TECH & ENG SOLUTIONS SANDIA LLC (US) | 2018-07-18 | — | — | EP | claimed |
| WO-2023079414-A1 | MULTIFUNCTIONAL FLUORINATED PHOSPHOROUS COMPOUNDS, METHODS OF MAKING, AND ARTICLES AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20080023108-A1 | METHOD OF FLUXING USING A FLUXING COMPOSITION CONTAINING COMPOUNDS WITH AN AROMATIC RING AND NO IMINO GROUP | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 2008-01-31 | — | — | US | disclosed |
| US-20060272747-A1 | Fluxing compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2006-12-07 | — | — | US | disclosed |
| EP-1728585-A1 | Fluxing compositions | National Starch and Chemical Investment Holding Corporation (US) | 2006-12-06 | — | — | EP | disclosed |