⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224332 | 0.78 | — | — | |
| SCHEMBL3144620 | 0.78 | NOS1 (0.42) | — | |
| SCHEMBL3150281 | 0.78 | NOS1 (0.41) | — | |
| SCHEMBL2123130 | 0.75 | NOS1 (0.41) | — | |
| SCHEMBL3279251 | 0.75 | NOS1 (0.44) | — | |
| SCHEMBL1680220 | 0.75 | — | — | |
| SCHEMBL6220651 | 0.74 | — | — | |
| SCHEMBL8292234 | 0.74 | — | — | |
| SCHEMBL1021803 | 0.74 | NOS1 (0.52) | — | |
| SCHEMBL14385408 | 0.74 | NOS1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725445-B2 | Cycloalkyl nitrile pyrazolo pyridones as Janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-08 | — | — | US | claimed |
| US-20160280704-A1 | CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-09-29 | — | — | US | claimed |
| EP-0851006-B1 | Organic pigment compositions | BAYER AG (US) | 2002-04-03 | — | — | EP | claimed |
| EP-0851006-A1 | Organic pigment compositions | Bayer Corporation (US) | 1998-07-01 | — | — | EP | claimed |
| US-5711800-A | Organic pigment compositions | BAYER CORPORATION (US) | 1998-01-27 | — | — | US | claimed |
| JP-10195326-A | — | — | None | — | — | JP | disclosed |
| EP-2976340-B1 | CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-06-13 | — | — | EP | disclosed |
| US-20170369446-A1 | MONOCYCLIC HETEROARYL COMPOUNDS | ARIAD PHARMA INC (US) | 2017-12-28 | — | — | US | disclosed |
| US-9725445-B2 | Cycloalkyl nitrile pyrazolo pyridones as Janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-08 | — | — | US | disclosed |
| US-9677220-B2 | Fluoropolymers and treatment agent | DAIKIN INDUSTRIES, LTD. (JP) | 2017-06-13 | — | — | US | disclosed |
| EP-1935292-B1 | Method of manufacturing a refrigerator door | HUSSMANN CORP (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20160280704-A1 | CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-09-29 | — | — | US | disclosed |
| US-20100068398-A1 | MERCHANDISERS HAVING ANTI-FOG COATINGS AND METHODS FOR MAKING THE SAME | HUSSMANN CORPORATION (US) | 2010-03-18 | — | — | US | disclosed |
| US-20100062152-A1 | MERCHANDISERS HAVING ANTI-FOG COATINGS AND METHODS FOR MAKING THE SAME | HUSSMANN CORPORATION (US) | 2010-03-11 | — | — | US | disclosed |
| US-20090149471-A1 | Monocyclic Heterocyclic Compounds | ARIAD PHARMACEUTICALS, INC. | 2009-06-11 | — | — | US | disclosed |
| US-20070003700-A1 | Merchandisers having anti-fog coatings and methods for making the same | HUSSMANN CORPORATION (US) | 2007-01-04 | — | — | US | disclosed |
| EP-0851006-B1 | Organic pigment compositions | BAYER AG (US) | 2002-04-03 | — | — | EP | disclosed |
| JP-H10195326-A | ORGANIC PIGMENT COMPOSITION | BAYER CORP | 1998-07-28 | — | — | JP | disclosed |
| EP-0851006-A1 | Organic pigment compositions | Bayer Corporation (US) | 1998-07-01 | — | — | EP | disclosed |
| US-5711800-A | Organic pigment compositions | BAYER CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |