SCHEMBL4121652

SCHEMBL4121652

O=P(O)(O)Cl.[PbH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123363 0.94
SCHEMBL10889963 0.94
SCHEMBL675599 0.89
SCHEMBL21693845 0.89 CA2 (0.42)
SCHEMBL9449476 0.89
Phosphoric Acid SCHEMBL9844682 0.89 CA2 (0.42)
SCHEMBL8506664 0.89
SCHEMBL9656970 0.89
SCHEMBL3153854 0.89
SCHEMBL2277991 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432387-A Soil restoration agent for phosphorus-rich sludge pyrolysis biochar combined phosphorus-dissolving bacteria as well as preparation method and application thereof 华中科技大学 2025-02-14 CN disclosed
CN-118479855-A Method for fixing waste incineration fly ash by utilizing ion adsorption type rare earth tailings 广东工业大学 2024-08-13 CN disclosed
CN-114644992-B Coxsackie strain and method for in-situ remediation of high-concentration heavy metal lead and uranium contaminated soil by same 有研资源环境技术研究院(北京)有限公司 2023-11-14 CN disclosed
CN-115417653-B Phosphogypsum synergistic acidic wastewater solidification stable fly ash and post-treatment method 中冶南方都市环保工程技术股份有限公司 2023-07-18 CN disclosed
CN-115417653-A Method for solidifying and stabilizing fly ash by cooperation of phosphogypsum and acid wastewater and post-treatment 中冶南方都市环保工程技术股份有限公司 2022-12-02 CN disclosed
CN-113024214-B Method for solidifying and stabilizing fly ash by cooperation of phosphogypsum and red mud 中冶南方都市环保工程技术股份有限公司 2022-09-02 CN disclosed
CN-113024214-B Method for solidifying and stabilizing fly ash by cooperation of phosphogypsum and red mud 中冶南方都市环保工程技术股份有限公司 2022-09-02 CN disclosed
CN-115004383-A Partially translucent photovoltaic window and method of making same 荷兰应用自然科学研究组织TNO 2022-09-02 CN disclosed
CN-114644992-A Strain of Coxsackia and method for in-situ remediation of high-concentration heavy metal lead and uranium contaminated soil by using same 有研资源环境技术研究院(北京)有限公司 2022-06-21 CN disclosed
CN-113750959-A Ferrihydrite @ bone charcoal material capable of synchronously fixing negative and positive heavy metal ions 同济大学 2021-12-07 CN disclosed
US-20030073728-A1 Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes METABASIS THERAPEUTICS, INC. 2003-04-17 US disclosed
US-6489476-B1 FRUCTOSE-1,6-BISPHOSPHATASE ENZYME INHIBITORS ARE USEFUL IN THE TREATMENT OF DIABETES AND OTHER CONDITIONS ASSOCIATED WITH ELEVATED BLOOD GLUCOSE OR EXCESS GLYCOGEN STORAGE. METABASIS THERAPEUTICS, INC. 2002-12-03 US disclosed
US-20020173490-A1 Novel bisamidate phosphonate prodrugs METABASIS THERAPEUTICS, INC. 2002-11-21 US disclosed
EP-1143955-A3 A COMBINATION OF FBPase INHIBITORS AND INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES Metabasis Therapeutics Inc. (US) 2002-08-28 EP disclosed
US-20020115899-A1 Reducing lead bioavailability NATIONAL UNIVERSITY OF SINGAPORE (SG) 2002-08-22 US disclosed
WO-2002003978-A2 A COMBINATION OF FBPase INHIBITORS AND ANTIDIABETIC AGENTS USEFUL FOR THE TREATMENT OF DIABETES METABASIS THERAPEUTICS, INC. (US) 2002-01-17 WO disclosed
EP-1143955-A2 A COMBINATION OF FBPase INHIBITORS AND INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES Metabasis Therapeutics Inc. (US) 2001-10-17 EP disclosed
EP-1112275-A1 NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE Metabasis Therapeutics, Inc. (US) 2001-07-04 EP disclosed
WO-2000038666-A2 A COMBINATION OF FBPase INHIBITORS AND INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES METABASIS THERAPEUTICS, INC. (US) 2000-07-06 WO disclosed
WO-2000014095-A1 NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE METABASIS THERAPEUTICS, INC. (US) 2000-03-16 WO disclosed