Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412216 | 0.89 | KMT2A (0.45) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL7904153 | 0.87 | L3MBTL1 (0.67) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL20738972 | 0.83 | L3MBTL1 (0.61) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL412609 | 0.82 | KMT2A (0.69) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL20738966 | 0.82 | KMT2A (0.69) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL16350036 | 0.82 | KMT2A (0.69) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31294486 | 0.81 | L3MBTL1 (0.58) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL16350091 | 0.80 | KMT2A (0.66) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL16350094 | 0.80 | KMT2A (0.66) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL411635 | 0.80 | KMT2A (0.58) | L3MBTL1KMT2APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871252-B2 | pH-responsive liposome | NANOTHETA CO, LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| US-20120064148-A1 | PH-RESPONSIVE LIPOSOME | BIONANOSHEETER CO., LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064148-A1 | PH-RESPONSIVE LIPOSOME | LIPA, SMPD3, SMPD1 | L3MBTL1 1139/4885KMT2A 2691/4885POLB 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.