Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.56 |
| ▸ | IDH1 | O75874 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113151 | 0.86 | EPHX2 (0.78) | EPHX2MEN1MAPTKMT2ARAB9A | |
| SCHEMBL4124694 | 0.85 | MAPT (0.75) | MEN1MAPTKMT2ATP53HTT | |
| SCHEMBL4113495 | 0.85 | EPHX2 (0.62) | EPHX2MEN1MAPTKMT2ATP53 | |
| SCHEMBL26156260 | 0.84 | EPHX2 (0.69) | EPHX2MEN1MAPTKMT2ATP53 | |
| SCHEMBL4117508 | 0.84 | MAPT (0.70) | MEN1MAPTKMT2ATP53RAB9A | |
| SCHEMBL4104388 | 0.83 | SMN1; SMN2 (0.64) | MEN1MAPTKMT2ATP53HTT | |
| SCHEMBL4104375 | 0.83 | RAB9A (0.71) | MEN1MAPTKMT2ATP53HTT | |
| SCHEMBL26154100 | 0.82 | EPHX2 (0.71) | EPHX2MEN1MAPTKMT2ATP53 | |
| SCHEMBL4105188 | 0.82 | MEN1 (0.59) | MEN1MAPTKMT2ATP53HTT | |
| SCHEMBL4123129 | 0.82 | KDR (0.59) | EPHX2MEN1MAPTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | EPHX2 2394/4885MEN1 3273/4885MAPT 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.