Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15677514 | 0.86 | ADRB2 (0.73) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4847807 | 0.84 | MAPT (0.68) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL14220132 | 0.84 | ADRB2 (0.78) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL10232110 | 0.83 | ADRB2 (0.70) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL8280495 | 0.83 | ADRB2 (0.70) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL28165793 | 0.83 | MAPT (0.69) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL20285625 | 0.83 | ADRB2 (0.70) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4869352 | 0.82 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL11744855 | 0.82 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL7724542 | 0.82 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308157-A2 | Therapeutic applications of beta-adrenergic agonists | The Rowett Research Institute (GB) | 1989-03-22 | — | — | EP | claimed |
| US-20090047336-A1 | NOVEL FORMULATION OF DEHYDRATED LIPID VESICLES FOR CONTROLLED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT VIA INHALATION | HONG KONG BAPTIST UNIVERSITY (CN) | 2009-02-19 | — | — | US | disclosed |
| EP-0370632-B1 | PHARMACEUTICAL SOLUTION CONTAINING SALBUTAMOL AND CROMOGLYCIC ACID | FISONS plc (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0370632-A1 | Pharmaceutical solution containing salbutamol and cromoglycic acid | FISONS plc (GB) | 1990-05-30 | — | — | EP | disclosed |