Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526051 | 0.98 | KDM4E (0.52) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL2781370 | 0.76 | KDM4E (0.85) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL11212983 | 0.74 | SREBF2 (0.82) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL11213828 | 0.74 | SREBF2 (0.82) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL95516 | 0.74 | KDM4E (0.53) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL242692 | 0.74 | RAB9A (0.58) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL1460934 | 0.74 | KDM4E (0.53) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL87128 | 0.74 | CYP3A4 (0.65) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL10475799 | 0.74 | KDM4E (0.53) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL27820489 | 0.74 | KDM4E (0.53) | KDM4EKMT2AARSREBF2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112294975-A | Contact allergen reagent combination and application thereof | 上海市皮肤病医院 | 2021-02-02 | — | — | CN | claimed |
| CN-112294975-A | Contact allergen reagent combination and application thereof | 上海市皮肤病医院 | 2021-02-02 | — | — | CN | disclosed |
| CN-105078773-A | Biodegradable compositions comprising renewably-based, biodegradable 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY LLC | 2015-11-25 | — | — | CN | disclosed |
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
| CN-101218201-A | Benzoic acid derivatives as GlyR modulators or agonists | ASTRAZENECA AB (SE) | 2008-07-09 | — | — | CN | disclosed |
| EP-1890993-A2 | BENZOIC ACID DERIVATIVES THAT ARE MODULATORS OR ANTAGONISTS OF GLYR | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006121390-A2 | BENZOIC ACID DERIVATIVES THAT ARE MODULATORS OR AGONISTS OF GLYR | ASTRAZENECA AB (SE) | 2006-11-16 | — | — | WO | disclosed |
| US-4242495-A | COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | GLRA1, GLRB, GPBAR1 | KDM4E 3259/4885KMT2A 2465/4885AR 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.