Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | HTT | P42858 | 5/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | DDX3X | O00571 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | BAZ1A | Q9NRL2 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4106750 | 0.84 | MEN1 (0.68) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL31125132 | 0.83 | MEN1 (0.73) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL4113183 | 0.82 | MAPT (0.70) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL31054229 | 0.81 | PPARA (0.58) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL4106349 | 0.81 | SAE1 (0.59) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL4111854 | 0.81 | MAPT (0.67) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL4122424 | 0.81 | CDK8 (0.56) | MEN1KMT2AMAPTCASP3SENP7 | |
| SCHEMBL4123109 | 0.80 | TSHR (0.71) | MEN1KMT2AMAPTHTTTP53 | |
| SCHEMBL1047211 | 0.79 | MEN1 (1.00) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL27877498 | 0.79 | MEN1 (0.75) | MEN1KMT2AMAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| EP-1804785-A2 | DIARYL UREAS AS CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006049941-A2 | DIARYL UREAS AS CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2006-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | MEN1 3273/4885KMT2A 2807/4885MAPT 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.