Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157251 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1LMNATDP1 | |
| SCHEMBL1131 | 0.97 | TSHR (0.40) | TSHRTHRBALDH1A1LMNATDP1 | |
| SCHEMBL10628008 | 0.94 | TSHR (0.47) | TSHRTHRBALDH1A1LMNASLC22A1 | |
| SCHEMBL25206988 | 0.93 | TSHR (0.38) | TSHRTHRBALDH1A1LMNATDP1 | |
| Phosphine SCHEMBL27559693 | 0.93 | TSHR (0.38) | TSHRTHRBALDH1A1LMNATDP1 | |
| SCHEMBL2465249 | 0.93 | TSHR (0.44) | TSHRTHRBALDH1A1LMNATDP1 | |
| SCHEMBL8911782 | 0.93 | TSHR (0.38) | TSHRTHRBALDH1A1LMNATDP1 | |
| SCHEMBL10851813 | 0.93 | TSHR (0.38) | TSHRTHRBALDH1A1LMNATDP1 | |
| Bromide SCHEMBL28239528 | 0.93 | TSHR (0.38) | TSHRTHRBALDH1A1LMNATDP1 | |
| SCHEMBL9716517 | 0.90 | TSHR (0.35) | TSHRTHRBALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112094282-B | Indole derivative-EDOT compound and preparation and application thereof | 浙江工业大学 | 2023-06-09 | — | — | CN | claimed |
| CN-112094282-A | Indole derivative-EDOT compound and preparation and application thereof | 浙江工业大学 | 2020-12-18 | — | — | CN | claimed |
| CN-112079840-A | Indole derivative-thiophene compound and preparation and application thereof | 浙江工业大学 | 2020-12-15 | — | — | CN | claimed |
| CN-112079849-A | Indole derivative-proEDOT compound and preparation and application thereof | 浙江工业大学 | 2020-12-15 | — | — | CN | claimed |
| CN-112210040-B | Wide-distribution polybutadiene-isoprene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-113563685-B | Formula sizing material of all-steel truck radial tire and preparation method thereof | 中国石油化工股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-112210128-B | Tire sidewall rubber material based on gradient block lithium BIR and preparation method thereof | 中国石油化工股份有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-112210127-B | High-performance rubber for radial tire tread base and preparation method thereof | 中国石油化工股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-112079840-B | Indole derivative-thiophene compound and preparation and application thereof | 浙江工业大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-112079849-B | Indole derivative-proEDOT compound and preparation and application thereof | 浙江工业大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-112210040-A | Wide-distribution polybutadiene-isoprene rubber and preparation method thereof | 中国石油化工股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-112210128-A | Tire sidewall rubber material based on gradient block lithium BIR and preparation method | 中国石油化工股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-112210127-A | High-performance rubber for radial tire tread base and preparation method thereof | 中国石油化工股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-112094282-A | Indole derivative-EDOT compound and preparation and application thereof | 浙江工业大学 | 2020-12-18 | — | — | CN | disclosed |
| CN-112079840-A | Indole derivative-thiophene compound and preparation and application thereof | 浙江工业大学 | 2020-12-15 | — | — | CN | disclosed |
| CN-112079849-A | Indole derivative-proEDOT compound and preparation and application thereof | 浙江工业大学 | 2020-12-15 | — | — | CN | disclosed |
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1939205-A1 | TRICYCLIC COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | FDFT1, COASY, HMGCR | TSHR 1672/4885THRB 1101/4885ALDH1A1 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.