Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL4123828

Brc1ccc(-c2ccc(Br)cc2)cc1.Brc1ccc(-c2ccc(Br)cc2)cc1.S

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.69
MAPK1 P28482 2/20 0.69
CYP2A6 P11509 1/20 0.67
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
ALOX15 P16050 2/20 0.47
NPC1 O15118 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
GAA P10253 2/20 0.40
TSHR P16473 2/20 0.40
CA1 P00915 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68094 0.96 ALDH1A1 (0.73) ALDH1A1MAPK1CYP2A6CA2CA12
SCHEMBL12302096 0.96 ALDH1A1 (0.73) ALDH1A1MAPK1CYP2A6CA2CA12
SCHEMBL1673427 0.96 ALDH1A1 (0.73) ALDH1A1MAPK1CYP2A6CA2CA12
SCHEMBL1255210 0.92 ALDH1A1 (0.69) ALDH1A1MAPK1CYP2A6CA2CA12
Water SCHEMBL3824552 0.92 ALDH1A1 (0.69) ALDH1A1MAPK1CYP2A6CA2CA12
Bromide SCHEMBL29066324 0.92 ALDH1A1 (0.69) ALDH1A1MAPK1CYP2A6CA2CA12
SCHEMBL21518323 0.92 ALDH1A1 (0.69) ALDH1A1MAPK1CYP2A6CA2CA12
Hydrogen Sulfide SCHEMBL27842395 0.87 CYP2A6 (0.89) ALDH1A1MAPK1CYP2A6CA2ALOX15
Hydrogen Sulfide SCHEMBL20295246 0.87 ALDH1A1 (0.94) ALDH1A1MAPK1CYP2A6CA2CA12
SCHEMBL17600463 0.85 ALDH1A1 (0.61) ALDH1A1MAPK1CYP2A6CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4210766-A BROMINATION OF 2-HALOPHENOLS CIBA-GEIGY CORPORATION (US) 1980-07-01 US claimed
JP-11080349-A None JP disclosed
JP-1033138-A None JP disclosed
CN-117865849-A Organic fluorescent small molecule based on diphenyl anthracene, preparation method and application thereof in organic electroluminescent device 吉林大学 2024-04-12 CN disclosed
CN-112521340-B Organic electroluminescent material and application thereof 北京八亿时空液晶科技股份有限公司 2023-04-04 CN disclosed
CN-114230580-B Multidentate organic ligand, preparation method and application thereof, metal supramolecular polymer and preparation method thereof 吉林大学 2023-01-24 CN disclosed
CN-112521343-B Organic electroluminescent material and device thereof 北京八亿时空液晶科技股份有限公司 2022-10-14 CN disclosed
CN-113402480-B Room-temperature phosphorescent material and preparation method and application thereof 吉林大学 2022-08-19 CN disclosed
CN-114436868-A Compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2022-05-06 CN disclosed
CN-114230580-A Multidentate organic ligand, preparation method and application thereof, metal supramolecular polymer and preparation method thereof 吉林大学 2022-03-25 CN disclosed
US-4841018-A Catalytic preparation of poly(arylene sulfide) from halothiophenol PHILLIPS PETROLEUM COMPANY (US) 1989-06-20 US disclosed
JP-S6433138-A PRODUCTION OF POLYPHENYLENE SULFIDE SEITETSU KAGAKU CO LTD 1989-02-03 JP disclosed
EP-0162606-B1 AROMATIC POLYTHIOETHERAMIDES AND PROCESS FOR THEIR PRODUCTION MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-01-25 EP disclosed
EP-0293692-A2 Polyarylene sulfide block copolymers, method for making, and use GENERAL ELECTRIC COMPANY (US) 1988-12-07 EP disclosed
US-4769424-A Polyarylene sulfide block copolymers, method for making, and use GENERAL ELECTRIC COMPANY (US) 1988-09-06 US disclosed
US-4621134-A Aromatic polythioetheramide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-11-04 US disclosed
EP-0179380-A1 Preparation of poly(arylene sulfide) PHILLIPS PETROLEUM COMPANY (US) 1986-04-30 EP disclosed
EP-0162606-A1 Aromatic polythioetheramides and process for their production MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1985-11-27 EP disclosed
US-4210766-A BROMINATION OF 2-HALOPHENOLS CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed