SCHEMBL4123832

SCHEMBL4123832

Brc1ccc(Sc2ccc(Br)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.64
MAOB P27338 3/20 0.64
CYP2A6 P11509 1/20 0.57
HAO1 Q9UJM8 1/20 0.48
MAPK1 P28482 3/20 0.47
TSHR P16473 2/20 0.47
NR1H2 P55055 1/20 0.47
CYP3A4 P08684 1/20 0.47
MCL1 Q07820 2/20 0.47
BCL2 P10415 1/20 0.47
LMNA P02545 1/20 0.43
ALDH1A1 P00352 2/20 0.42
ALOX15 P16050 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3411276 1.00 MAOA (0.64) MAOAMAOBCYP2A6HAO1MAPK1
SCHEMBL8588228 0.91 MAOA (0.56) MAOAMAOBCYP2A6HAO1MAPK1
SCHEMBL10899441 0.91 MAOA (0.56) MAOAMAOBCYP2A6HAO1MAPK1
SCHEMBL2414029 0.88 MAOA (0.54) MAOAMAOBCYP2A6HAO1MAPK1
SCHEMBL9475276 0.86 MAOA (0.55) MAOAMAOBCYP2A6HAO1MAPK1
SCHEMBL9418077 0.86 MAPK1 (0.74) MAOAMAOBCYP2A6HAO1MAPK1
SCHEMBL8142821 0.86 MAOA (0.52) MAOAMAOBCYP2A6HAO1MCL1
SCHEMBL8142840 0.86 MAOA (0.52) MAOAMAOBCYP2A6HAO1MAPK1
SCHEMBL4979446 0.86 MAPK1 (0.74) MAOAMAOBCYP2A6HAO1MAPK1
SCHEMBL7938361 0.86 NR1H2 (0.74) MAOAMAOBCYP2A6HAO1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371674-A Preparation method of donor-acceptor type metal organic framework photocatalyst and application of photocatalytic amine oxide/thioether 长沙理工大学 2025-01-28 CN claimed
CN-118064908-A Method for realizing efficient and green electrocatalytic thioether oxidation through tetraminocobalt complex 大连理工大学 2024-05-24 CN claimed
CN-115141814-B Application of 4-hydroxyacetophenone monooxygenase 江南大学 2023-05-05 CN claimed
CN-105728043-B A kind of polyacid@alumina composite catalysis materials and preparation method thereof 北京化工大学 2018-07-27 CN claimed
CN-106674067-A Method for compounding sulfur-difluoromethylene compound from thiol 南京理工大学 2017-05-17 CN claimed
CN-104961694-A Diphenyl sulfide compound displaced with double triazole and preparing method and application thereof UNIV TIANJIN NORMAL 2015-10-07 CN claimed
US-5929171-A CORE BEING COMPOSED OF A RUBBER COMPOSITION CONTAINING A BASE RUBBER, A METAL SALT OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACID, A CO-CROSSLINKING INITIATOR, AND A SPECIFIC ORGANOSULFUR COMPOUND; IMPROVED FLIGHT DISTANCE, DURABILITY SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-07-27 US claimed
US-5576417-A Method for synthesizing aromatic polymers DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-11-19 US claimed
US-5268449-A Containing arylene sulfide and arylene sulfonate segments PHILLIPS PETROLEUM COMPANY (US) 1993-12-07 US claimed
US-4210766-A BROMINATION OF 2-HALOPHENOLS CIBA-GEIGY CORPORATION (US) 1980-07-01 US claimed
JP-11080349-A None JP disclosed
JP-1033138-A None JP disclosed
WO-2025105341-A1 METAL PATTERNING MATERIAL, PENTAFLUOROSULFANYL COMPOUND, METAL PATTERNING THIN FILM, ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC APPARATUS, AND METAL PATTERN FORMING METHOD 東ソー株式会社 2025-05-22 WO disclosed
CN-116283684-B Green preparation method of diphenyl sulfide and derivative thereof 常州大学 2025-04-08 CN disclosed
CN-119192845-B Preparation method of high-temperature-resistant high-heat-conductivity PPS composite material 东莞市普万光电散热科技有限公司 2025-03-14 CN disclosed
EP-0140324-A2 Polyarylene sulfides with reduced corrosiveness BAYER AG (DE) 1985-05-08 EP disclosed
EP-0121206-A2 Process for preparing poly(arylene sulfides) which may be branched BAYER AG (DE) 1984-10-10 EP disclosed
US-4339611-A BUTANOL, BUTANAL, COBALT, IODINE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-07-13 US disclosed
US-4210766-A BROMINATION OF 2-HALOPHENOLS CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed