Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.72 |
| ▸ | NPC1 | O15118 | 11/20 | 0.72 |
| ▸ | GBA1 | P04062 | 10/20 | 0.72 |
| ▸ | MAPT | P10636 | 8/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403090 | 0.82 | RAB9A (0.76) | RAB9ANPC1GBA1MAPTSMN1; SMN2 | |
| SCHEMBL4126159 | 0.81 | POLB (0.55) | RAB9ANPC1GBA1MAPTSMN1; SMN2 | |
| SCHEMBL4118526 | 0.80 | MAPT (0.66) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4124271 | 0.79 | RAB9A (0.64) | RAB9ANPC1MAPTSMN1; SMN2TSHR | |
| SCHEMBL4116166 | 0.79 | MAPT (0.58) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1142765 | 0.79 | RAB9A (1.00) | RAB9ANPC1GBA1MAPTSMN1; SMN2 | |
| SCHEMBL14353530 | 0.78 | RAB9A (1.00) | RAB9ANPC1GBA1MAPTSMN1; SMN2 | |
| SCHEMBL4118244 | 0.78 | MAPT (0.59) | MAPTSMN1; SMN2TSHRTP53MEN1 | |
| SCHEMBL4110177 | 0.78 | NPC1 (0.52) | RAB9ANPC1MAPTSMN1; SMN2TSHR | |
| SCHEMBL14785039 | 0.78 | MAPT (0.47) | RAB9ANPC1GBA1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | RAB9A 815/4885NPC1 927/4885GBA1 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.