Piperidine

Piperidine

SCHEMBL4124279

C1CCNCC1.CCOC(C)=O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.61
LMNA P02545 1/20 0.61
HSD17B10 Q99714 1/20 0.61
TSHR P16473 1/20 0.40
OPRM1 P35372 1/20 0.37
ALOX15 P16050 2/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
TRPA1 O75762 1/20 0.33
GLO1 Q04760 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL27915255 0.98 ALDH1A1 (0.58) ALDH1A1LMNAHSD17B10TSHROPRM1
Ethyl Acetate SCHEMBL28224693 0.98 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10TSHROPRM1
Ethyl Acetate SCHEMBL28024376 0.91 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TSHROPRM1
Piperazine SCHEMBL6093828 0.89 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHROPRM1
Piperazine SCHEMBL27792846 0.86 ALDH1A1 (0.67) ALDH1A1LMNAHSD17B10TSHROPRM1
Cyclohexane SCHEMBL509143 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL416739 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL509553 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL5908851 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL1172967 0.86 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117845051-A Temperature-control type hydrophobic extractant for homogeneously separating gold (III), preparation method thereof and extraction method thereof 山东大学 2024-04-09 CN claimed
CN-101809015-A Salts of CGRP antagonists, method for the production thereof and use thereof as medicaments BOEHRINGER INGELHEIM INT 2010-08-18 CN claimed
CN-117845051-B Temperature-control type hydrophobic extractant for homogeneously separating gold (III), preparation method thereof and extraction method thereof 山东大学 2026-04-10 CN disclosed
CN-117845051-A Temperature-control type hydrophobic extractant for homogeneously separating gold (III), preparation method thereof and extraction method thereof 山东大学 2024-04-09 CN disclosed
CN-117845051-A Temperature-control type hydrophobic extractant for homogeneously separating gold (III), preparation method thereof and extraction method thereof 山东大学 2024-04-09 CN disclosed
CN-101809015-A Salts of CGRP antagonists, method for the production thereof and use thereof as medicaments BOEHRINGER INGELHEIM INT 2010-08-18 CN disclosed
US-20090181942-A1 TRICYCLIC COMPOUNDS DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-07-16 US disclosed
US-20090036469-A1 2,6-SUBSTITUTED-4-MONOSUBSTITUTED AMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS SANOFI-AVENTIS (FR) 2009-02-05 US disclosed
EP-1699753-A4 IMPROVED PROCESS FOR THE PREPARATION OF ENTACAPONE SUVEN LIFE SCIENCES LTD (IN) 2008-12-31 EP disclosed
EP-1939205-A1 TRICYCLIC COMPOUND Daiichi Sankyo Company, Limited (JP) 2008-07-02 EP disclosed
WO-2008039882-A1 A COMBINATION OF NIACIN AND A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST SANOFI-AVENTIS U.S. LLC (US) 2008-04-03 WO disclosed
EP-1699753-A1 IMPROVED PROCESS FOR THE PREPARATION OF ENTACAPONE Suven Life Sciences Limited (IN) 2006-09-13 EP disclosed
WO-2005063693-A1 IMPROVED PROCESS FOR THE PREPARATION OF ENTACAPONE SUVEN LIFE SCIENCES LTD (IN) 2005-07-14 WO disclosed
US-6361940-B1 IMMOBILIZATION; GENETIC ENGINEERING QIAGEN GENOMICS, INC. 2002-03-26 US disclosed
CN-1305470-A Amidine compounds JAPAN TOBACCO INC (JP) 2001-07-25 CN disclosed
CN-1021733-C Process for preparation of indolylpiperidine compounds FUJISAWA PHARMACEUTICAL CO (JP) 1993-08-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036469-A1 2,6-SUBSTITUTED-4-MONOSUBSTITUTED AMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS PTGDR2, PTGDR, PTGER2 ALDH1A1 802/4885LMNA 4152/4885HSD17B10 1487/4885
US-20090181942-A1 TRICYCLIC COMPOUNDS FDFT1, COASY, HMGCR ALDH1A1 1587/4885LMNA 1109/4885HSD17B10 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.