Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTR1E | P28566 | 2/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29582859 | 0.89 | EPHX2 (0.50) | EPHX2MAPTMEN1KMT2ALMNA | |
| SCHEMBL17737538 | 0.82 | IDO1 (0.58) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL20838723 | 0.82 | IDO1 (0.51) | EPHX2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20852663 | 0.82 | IDO1 (0.51) | EPHX2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17737122 | 0.82 | IDO1 (0.51) | EPHX2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17737121 | 0.82 | IDO1 (0.51) | EPHX2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20838737 | 0.82 | IDO1 (0.58) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL17737066 | 0.82 | IDO1 (0.58) | MAPTMEN1KMT2ALMNAGAA | |
| Hydrochloric Acid SCHEMBL7810311 | 0.81 | KMT2A (0.58) | KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL28771680 | 0.81 | TSHR (0.47) | EPHX2MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227480-B2 | Indazole derivative having spiro ring structure in side chain | UBE INDUSTRIES, LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20090170887-A1 | Novel indazole derivative having spiro ring structure in side chain | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-2025676-A1 | NOVEL INDAZOLE DERIVATIVE HAVING SPIRO RING STRUCTURE IN SIDE CHAIN | Ube Industries, Ltd. (JP) | 2009-02-18 | — | — | EP | disclosed |
| EP-1016653-B1 | Preparation of high-dye yield couplers and intermediates useful therein | EASTMAN KODAK CO (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6172260-B1 | Preparation of high dye-yield couplers and intermediates useful therein | EASTMAN KODAK COMPANY | 2001-01-09 | — | — | US | disclosed |
| US-6132944-A | A FORMED CARBAMYLOXY GROUP OR A SULFONYLISOCYANATO GROUP LINKED A COUPLER AND A DYE; EXHIBIT A HIGHER REACTIVITY WITH OXIDIZED DEVELOPER | EASTMAN KODAK COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1016916-A1 | Photographic element containing high dye-yield couplers | EASTMAN KODAK COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-1016653-A1 | Preparation of high-dye yield couplers and intermediates useful therein | EASTMAN KODAK COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170887-A1 | Novel indazole derivative having spiro ring structure in side chain | CIT, ROCK1, ROCK2 | EPHX2 1627/4885MAPT 4450/4885MEN1 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.