SCHEMBL4124570

SCHEMBL4124570

CC(C)(C)c1ccc2ccccc2c1C(C)(C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.46
ALDH1A1 P00352 6/20 0.46
TSHR P16473 5/20 0.46
CYP2A6 P11509 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
HPRT1 P00492 1/20 0.42
CYP1A2 P05177 2/20 0.40
HIF1A Q16665 3/20 0.39
CYP1B1 Q16678 1/20 0.39
HPGD P15428 4/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
CYP3A4 P08684 2/20 0.38
KEAP1 Q14145 1/20 0.38
MAPT P10636 2/20 0.38
ATM Q13315 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
GLA P06280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9624177 0.98 HSD17B10 (0.44) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL15910482 0.98 HSD17B10 (0.44) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL15910481 0.98 HSD17B10 (0.44) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL11954796 0.86 HSD17B10 (0.43) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL22760235 0.86 HSD17B10 (0.42) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL3420318 0.82 ALDH1A1 (0.40) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL354096 0.80 ALDH1A1 (0.39) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL1906196 0.80 HSD17B10 (0.48) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL2873053 0.78 CYP2A6 (0.56) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL2873052 0.78 TSHR (0.56) HSD17B10ALDH1A1TSHRCYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146479-A1 A METHOD FOR PURIFICATION OF ORGANIC WATER-SOLUBLE POLYMERS FROM HYDROPHOBIC CONTAMINANTS USTAV EXPERIMENTALNEJ FYZIKY SLOVENSKEJ AKADEMIE VIED, VEREJNA VYSKUMNA INSTITUCIA (SK) 2023-08-03 WO claimed
EP-4219603-A1 A METHOD FOR PURIFICATION OF ORGANIC WATER-SOLUBLE POLYMERS FROM HYDROPHOBIC CONTAMINANTS Ustav experimentálnej fyziky SAV, v.v.i. (SK) 2023-08-02 EP claimed
CN-109433253-A The catalyst and its preparation method and application of 2,6- di-t-butyl naphthalin is prepared for naphthalene form selected methylation 中国科学院大连化学物理研究所 2019-03-08 CN claimed
CN-105829282-B Method for producing phthalimide 朗盛德国有限责任公司 2018-08-28 CN claimed
EP-3083558-B1 PROCESS FOR THE PRODUCTION OF PHTHALIMIDES LANXESS DEUTSCHLAND GMBH (DE) 2017-11-15 EP claimed
US-9701632-B2 Process for the production of phthalimides LANXESS DEUTSCHLAND GMBH (DE) 2017-07-11 US claimed
US-20160304454-A1 PROCESS FOR THE PRODUCTION OF PHTHALIMIDES LANXESS DEUTSCHLAND GMBH (DE) 2016-10-20 US claimed
CN-105829282-A Process for production of phthalimides 朗盛德国有限责任公司 2016-08-03 CN claimed
CN-101417944-B Method for preparing 2,6-naphthalenedicarboxylic acid from 2,6-di-t-butyl naphthalin DALIAN CHEMICAL PHYSICS INST 2012-07-11 CN claimed
JP-55103437-A None JP disclosed
CN-118084598-B Synthesis method of 2, 6-dialkyl naphthalene 信诺立兴(沧州渤海新区)化工有限公司 2024-12-17 CN disclosed
CN-118084598-A Synthesis method of 2, 6-dialkyl naphthalene 信诺立兴(沧州渤海新区)化工有限公司 2024-05-28 CN disclosed
WO-2023146479-A1 A METHOD FOR PURIFICATION OF ORGANIC WATER-SOLUBLE POLYMERS FROM HYDROPHOBIC CONTAMINANTS USTAV EXPERIMENTALNEJ FYZIKY SLOVENSKEJ AKADEMIE VIED, VEREJNA VYSKUMNA INSTITUCIA (SK) 2023-08-03 WO disclosed
EP-4219603-A1 A METHOD FOR PURIFICATION OF ORGANIC WATER-SOLUBLE POLYMERS FROM HYDROPHOBIC CONTAMINANTS Ustav experimentálnej fyziky SAV, v.v.i. (SK) 2023-08-02 EP disclosed
EP-0268400-A1 Steroidal 17alpha-silyl ethers and process to corticoids and progesterones THE UPJOHN COMPANY (US) 1988-05-25 EP disclosed
WO-1988003534-A1 STEROIDAL 17alpha-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES THE UPJOHN COMPANY (US) 1988-05-19 WO disclosed
EP-0234394-A2 Highly concentrated stable solutions of dyes BAYER AG (DE) 1987-09-02 EP disclosed
EP-0058430-B1 DYESTUFF-CONTAINING MICROSCOPIC CAPSULE DISPERSION FOR RECORD MATERIALS MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-12-04 EP disclosed
US-4384871-A Dyestuff-containing microscopic capsule dispersion for record materials MITSUI TOATSU CHEMICALS, INC. (JP) 1983-05-24 US disclosed
JP-S55103437-A PRESSURE MEASURING SHEET FUJI PHOTO FILM CO LTD 1980-08-07 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304454-A1 PROCESS FOR THE PRODUCTION OF PHTHALIMIDES SLC16A7, PAH, DDT HSD17B10 1020/4885ALDH1A1 1642/4885TSHR 3995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.