SCHEMBL4125

SCHEMBL4125

[NH]c1ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7557143 0.69 KDM4E (0.50)
Dipyridyl SCHEMBL3711450 0.67 KDM4E (1.00)
Dipyridyl SCHEMBL29351528 0.67 KDM4E (1.00)
Dipyridyl SCHEMBL5922 0.67 KDM4E (1.00)
Dipyridyl SCHEMBL29907716 0.67 KDM4E (1.00)
SCHEMBL4282144 0.67 KDM4E (0.48)
SCHEMBL2705582 0.67
SCHEMBL232601 0.65
Dipyridyl SCHEMBL183651 0.65 KDM4E (0.93)
Dipyridyl SCHEMBL9644480 0.65 KDM4E (0.93)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8115 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043636-B2 Method for producing triarylorganoborates COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-07-23 US claimed
WO-2024145245-A2 ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2024-07-04 WO claimed
CN-115057855-B Substituted five-membered and six-membered heterocyclic compound, preparation method, pharmaceutical composition and application thereof 厦门大学 2024-04-26 CN claimed
US-20240092773-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES UCB Biopharma SRL (BE) 2024-03-21 US claimed
CN-117624030-A Bidentate pyridinylamino ligand hafnium catalyst, preparation method and application thereof 中国科学技术大学 2024-03-01 CN claimed
CN-117466897-A Highly selective FGFR2 inhibitors 深圳福沃药业有限公司 2024-01-30 CN claimed
WO-2023235719-A2 STEREOSELECTIVE ALLOSTERIC INHIBITORS OF SARM1 THE SCRIPPS RESEARCH INSTITUTE (US) 2023-12-07 WO claimed
CN-117050056-A Substituted quinoline-4-carboxamide compound and preparation method and application thereof 中国医学科学院药物研究所 2023-11-14 CN claimed
CN-116987032-A 4-piperazine amide benzenesulfonamide-1, 8-naphthalimide derivative, and preparation method and application thereof 桂林医学院 2023-11-03 CN claimed
CN-116903628-A FGFR2 inhibitors and methods of use 深圳福沃药业有限公司 2023-10-20 CN claimed
US-4333932-A DIHYDROISOINDOLES, HYPOGLYCEMIC, ANTIDIABETIC PFIZER INC. (US) 1982-06-08 US claimed
WO-1982000400-A1 METHOD FOR SELECTIVELY CONTROLLING GRASSY WEEDS IN RICE SMITH L 1982-02-18 WO claimed
EP-0010896-B1 ORGANIC DIAMINE COMPOUNDS FOR USE AS ORAL HYPOGLYCEMIC AGENTS AND PHARMACEUTICAL COMPOSITIONS THEREOF PFIZER INC. (US) 1981-12-30 EP claimed
EP-0004904-B1 2-AMINO-3A,4,5,6-TETRAHYDROPERIMIDINE DERIVATIVES, MEDICAMENTS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1981-07-29 EP claimed
EP-0010896-A1 Organic diamine compounds for use as oral hypoglycemic agents and pharmaceutical compositions thereof PFIZER INC. (US) 1980-05-14 EP claimed
US-4199346-A Herbicides based on 2-dibenzofuranyloxyalkanecarboxylic acid derivatives AMERICAN HOECHST CORPORATION (US) 1980-04-22 US claimed
EP-0004904-A1 2-Amino-3a,4,5,6-tetrahydroperimidine derivatives, medicaments containing them and process for their preparation BAYER AG (DE) 1979-10-31 EP claimed
US-4132436-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1979-01-02 US claimed
US-4119777-A BY OXIDATION OF A THIOAMIDE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1978-10-10 US claimed
US-4016263-A BACTERICIDES BOEHRINGER INGELHEIM GMBH (DT) 1977-04-05 US claimed