Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 18/20 | 0.61 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935802 | 0.88 | CXCR4 (0.70) | CXCR4FNTAFNTB | |
| SCHEMBL3998366 | 0.84 | CXCR4 (0.66) | CXCR4FNTAFNTB | |
| SCHEMBL3993664 | 0.84 | CXCR4 (0.73) | CXCR4 | |
| SCHEMBL3990678 | 0.84 | CXCR4 (0.73) | CXCR4 | |
| SCHEMBL4935750 | 0.84 | CXCR4 (0.65) | CXCR4FNTAFNTB | |
| SCHEMBL3993002 | 0.84 | CXCR4 (0.75) | CXCR4 | |
| SCHEMBL3993008 | 0.84 | CXCR4 (0.75) | CXCR4 | |
| SCHEMBL4940845 | 0.84 | CXCR4 (0.75) | CXCR4 | |
| SCHEMBL4940859 | 0.84 | CXCR4 (0.75) | CXCR4 | |
| SCHEMBL3993514 | 0.84 | CXCR4 (0.75) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778231-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1778231-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020415-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |