Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 18/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687761 | 0.80 | PTGER4 (0.74) | PTGER4FFAR1 | |
| SCHEMBL12991934 | 0.80 | PTGER4 (0.62) | PTGER4FFAR1CA1CA2 | |
| Hydrochloric Acid SCHEMBL3536482 | 0.80 | PTGER4 (0.73) | PTGER4FFAR1 | |
| SCHEMBL3532327 | 0.79 | PTGER4 (0.81) | PTGER4 | |
| Trifluoroacetic Acid SCHEMBL3540222 | 0.75 | PTGER4 (0.58) | PTGER4FFAR1CA1CA2 | |
| SCHEMBL4125882 | 0.75 | PTGER4 (0.47) | PTGER4FFAR1CA1CA2 | |
| Bgc-20-1531 Free Base SCHEMBL29433722 | 0.68 | PTGER4 (1.00) | PTGER4 | |
| Bgc-20-1531 Free Base SCHEMBL2348089 | 0.68 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL3537964 | 0.68 | PTGER4 (0.82) | PTGER4 | |
| SCHEMBL3534547 | 0.68 | PTGER4 (0.82) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143437-A1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LIMITED (GB) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143437-A1 | EP4 RECEPTOR ANTAGONISTS | PTGER4, NR4A1, NR4A2 | PTGER4 1/4885FFAR1 268/4885CA1 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.