Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.65 |
| ▸ | AXL | P30530 | 5/20 | 0.60 |
| ▸ | MAP3K11 | Q16584 | 4/20 | 0.53 |
| ▸ | TNIK | Q9UKE5 | 8/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113498 | 0.90 | AXL (0.62) | MAP4K1AXLMAP3K11TNIKCHEK1 | |
| SCHEMBL4121233 | 0.89 | MAP3K11 (0.67) | MAP4K1AXLMAP3K11TNIK | |
| SCHEMBL28901919 | 0.88 | MAP4K1 (0.62) | MAP4K1MAP3K11TNIKCHEK1ACHE | |
| Hydrochloric Acid SCHEMBL4114342 | 0.86 | MAP4K1 (0.59) | MAP4K1AXLMAP3K11TNIKCHEK1 | |
| SCHEMBL4123805 | 0.86 | AXL (0.57) | MAP4K1AXL | |
| SCHEMBL5430498 | 0.85 | NR4A2 (0.60) | MAP4K1CHEK1 | |
| Hydrochloric Acid SCHEMBL4126148 | 0.82 | MAP4K1 (0.53) | MAP4K1AXLMAP3K11TNIKCHEK1 | |
| SCHEMBL29042029 | 0.82 | AXL (0.58) | MAP4K1AXL | |
| SCHEMBL30508265 | 0.82 | AXL (0.58) | MAP4K1AXL | |
| SCHEMBL16343639 | 0.80 | MAP4K1 (0.64) | MAP4K1MAP3K11TNIKCHEK1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018130-A1 | Derivatives of 5-Aryl-1H-Pyrrolo [2, 3B] Pyridine-3-Carboxamide or 5-Aryl-1H-Pyrrolo [2, 3B] Pyridine-3-Carboxylic Acid | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | US | claimed |
| US-20090018130-A1 | Derivatives of 5-Aryl-1H-Pyrrolo [2, 3B] Pyridine-3-Carboxamide or 5-Aryl-1H-Pyrrolo [2, 3B] Pyridine-3-Carboxylic Acid | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | US | disclosed |
| EP-1761530-A1 | NEW DERIVATIVES OF 5-ARYL-1H-PYRROLO [2, 3B] PYRIDINE-3-CARBOXAMIDE OR 5-ARYL-1H-PYRROLO [2, 3B] PYRIDINE-3-CARBOXYLIC ACID | AstraZeneca AB (SE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006001754-A1 | NEW DERIVATIVES OF 5-ARYL-1H-PYRROLO [2, 3B] PYRIDINE-3-CARBOXAMIDE OR 5-ARYL-1H-PYRROLO [2, 3B] PYRIDINE-3-CARBOXYLIC ACID | ASTRAZENECA AB (SE) | 2006-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018130-A1 | Derivatives of 5-Aryl-1H-Pyrrolo [2, 3B] Pyridine-3-Carboxamide or 5-Aryl-1H-Pyrrolo [2, 3B] Pyridine-3-Carboxylic Acid | AADAC, PAH, PDE7A | MAP4K1 939/4885AXL 2020/4885MAP3K11 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.