Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126262 | 1.00 | GPR119 (0.39) | GPR119CETPACHEFAAHJAK2 | |
| SCHEMBL4126259 | 1.00 | GPR119 (0.39) | GPR119CETPACHEFAAHJAK2 | |
| SCHEMBL4134831 | 1.00 | GPR119 (0.39) | GPR119CETPACHEFAAHJAK2 | |
| SCHEMBL4134833 | 1.00 | GPR119 (0.39) | GPR119CETPACHEFAAHJAK2 | |
| SCHEMBL4121939 | 0.85 | GPR119 (0.44) | GPR119CETPACHEFAAH | |
| SCHEMBL4121931 | 0.85 | GPR119 (0.44) | GPR119CETPACHEFAAH | |
| SCHEMBL4126112 | 0.85 | GPR119 (0.44) | GPR119CETPACHEFAAH | |
| SCHEMBL4129994 | 0.83 | GPR119 (0.39) | GPR119CETPACHEJAK2JAK1 | |
| SCHEMBL4126674 | 0.83 | CCNC (0.42) | GPR119CETPACHEFAAHJAK2 | |
| SCHEMBL4129996 | 0.83 | GPR119 (0.39) | GPR119CETPACHEJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | GPR119 122/4885CETP 3157/4885ACHE 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.