Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126878 | 0.88 | PTGDR (0.44) | PRKDCMAPTALDH1A1HIF1APTGDR | |
| SCHEMBL20471984 | 0.82 | GAA (0.55) | PRKDCMAPTP2RY12KDM4EALDH1A1 | |
| SCHEMBL8088529 | 0.81 | PRKDC (0.57) | PRKDCMAPTKDM4EALDH1A1HTT | |
| SCHEMBL14339148 | 0.74 | PRKDC (0.73) | PRKDCMAPTKDM4EALDH1A1HTT | |
| SCHEMBL600210 | 0.74 | PRKDC (1.00) | PRKDCMAPTKDM4EALDH1A1HTT | |
| SCHEMBL29776854 | 0.74 | PRKDC (1.00) | PRKDCMAPTKDM4EALDH1A1HTT | |
| SCHEMBL6121031 | 0.74 | FLT3 (0.47) | MAPTKDM4EALDH1A1HTTKMT2A | |
| SCHEMBL8260769 | 0.72 | PRKDC (0.71) | PRKDCMAPTKDM4EALDH1A1HTT | |
| SCHEMBL30590429 | 0.72 | PRKDC (0.71) | PRKDCMAPTKDM4EALDH1A1HTT | |
| SCHEMBL14551894 | 0.72 | PRKDC (0.71) | PRKDCMAPTKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | PRKDC 4866/4885MAPT 4157/4885P2RY12 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.